Mefloquine in the treatment of progressive multifocal leukoencephalopathy

Mefloquine, an antimalarial medication with efficacy against JC virus, was used to treat progressive multifocal leukoencephalopathy. A 54-year-old woman with sarcoidosis presented with a progressive cerebellar syndrome. MRI showed lesions affecting the right cerebellum that progressed over time to t...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2011-04, Vol.82 (4), p.452-455
Hauptverfasser:	Gofton, T E, Al-Khotani, A, O'Farrell, B, Ang, L C, McLachlan, R S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Ataxia Biological and medical sciences Biopsy Cerebrospinal Fluid - virology Decision making Deoxyribonucleic acid DNA Drug dosages Drug resistance Enzymes Family medical history Female HIV Human immunodeficiency virus Human viral diseases Humans Infections Infectious diseases JC virus JC Virus - drug effects leukoencephalopathy Leukoencephalopathy, Progressive Multifocal - drug therapy Leukoencephalopathy, Progressive Multifocal - virology Liver Magnetic Resonance Imaging - methods Medical sciences mefloquine Mefloquine - therapeutic use Middle Aged Nausea Neurology NMR Nuclear magnetic resonance Patients Progressive multifocal leukoencephalopathy Sarcoidosis Steroids Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral infections Vomiting
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