YAP is a candidate oncogene for esophageal squamous cell carcinoma

Yes-associated protein (YAP), the nuclear effector of the Hippo pathway, is a key regulator of organ size and a candidate human oncogene located at chromosome 11q22. Since we previously reported amplification of 11q22 region in esophageal squamous cell carcinoma (ESCC), in this study we focused on t...

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Veröffentlicht in:	Carcinogenesis (New York) 2011-03, Vol.32 (3), p.389-398
Hauptverfasser:	MURAMATSU, Tomoki, IMOTO, Issei, MATSUI, Takeshi, KOZAKI, Ken-Ichi, HARUKI, Shigeo, SUDOL, Marius, SHIMADA, Yutaka, TSUDA, Hitoshi, KAWANO, Tatsuyuki, INAZAWA, Johji
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Blotting, Western Carcinogenesis, carcinogens and anticarcinogens Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Cell Line, Tumor Cell Nucleus - genetics Cell Nucleus - metabolism Cell Proliferation Cyclin-Dependent Kinase Inhibitor p21 - genetics Cyclin-Dependent Kinase Inhibitor p21 - metabolism Esophageal Neoplasms - genetics Esophageal Neoplasms - metabolism Esophageal Neoplasms - pathology Esophagus Fluorescent Antibody Technique Gastroenterology. Liver. Pancreas. Abdomen Humans Immunoenzyme Techniques Inhibitor of Apoptosis Proteins - genetics Inhibitor of Apoptosis Proteins - metabolism Medical sciences Nuclear Proteins - antagonists & inhibitors Nuclear Proteins - genetics Nuclear Proteins - metabolism Oncogenes Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Small Interfering - genetics Transcription Factors - antagonists & inhibitors Transcription Factors - genetics Transcription Factors - metabolism Tumor Stem Cell Assay Tumors
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