Low Levels of NF-B/p65 Mark Anergic CD4+ T Cells and Correlate with Disease Severity in Sarcoidosis

T lymphocytes from patients with sarcoidosis respond weakly when stimulated with mitogen or antigen. However, the mechanisms responsible for this anergy are not fully understood. Here, we investigated the protein levels of nuclear transcription factor NF-B (p50, p65, and p105), IB (inhibitor of NF-B...

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Veröffentlicht in:Clinical and vaccine immunology 2011-02, Vol.18 (2), p.223-234
Hauptverfasser: Lee, Nam-Sihk, Barber, Laura, Kanchwala, Ali, H Childs, Carter J, Kataria, Yash P, Judson, Marc A, Mazer, Mark A, Arce, Sergio
Format: Artikel
Sprache:eng
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