Neural Substrates of Affective Face Recognition in Alexithymia: A Functional Magnetic Resonance Imaging Study
Background: Alexithymia is a condition characterized by deficits in cognitive processing and the regulation of emotions. Several theories have been proposed for the underlying neurobiology, but the etiology of alexithymia remains unclear. Methods: Using functional magnetic resonance imaging, we inve...
Gespeichert in:
| Veröffentlicht in: | Neuropsychobiology 2011-01, Vol.63 (2), p.119-124 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 124 |
|---|---|
| container_issue | 2 |
| container_start_page | 119 |
| container_title | Neuropsychobiology |
| container_volume | 63 |
| creator | Lee, Byeong-Taek Lee, Hwa-Young Park, Sae-Ah Lim, Jin-Young Tae, Woo Suk Lee, Min-Soo Joe, Sook-Haeng Jung, In-Kwa Ham, Byung-Joo |
| description | Background: Alexithymia is a condition characterized by deficits in cognitive processing and the regulation of emotions. Several theories have been proposed for the underlying neurobiology, but the etiology of alexithymia remains unclear. Methods: Using functional magnetic resonance imaging, we investigated brain activation measured on the scale of alexithymia in 38 individuals who were presented with neutral, sad, or angry affective facial stimuli. Results: We found significant inverse correlations between the degree of alexithymia represented by the Korean version of the Toronto Alexithymia Scale (TAS-20K) and the intensity of the neural response to angry facial stimuli over neutral facial stimuli in the right caudate. This result was mainly due to the activations in factor 2 (difficulty describing feelings) in TAS-20K scale. Conclusions: The results suggest that functional impairments in the caudate of the fronto-striatal circuitry may play important roles in the pathophysiology of alexithymia. |
| doi_str_mv | 10.1159/000318086 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_907156108</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>907156108</sourcerecordid><originalsourceid>FETCH-LOGICAL-c430t-1ac6a8589a3d8bd1c69075c60cd52ecc383925c5b5a836ae4d60ec75a60db3943</originalsourceid><addsrcrecordid>eNqF0c1rFDEYBvAgil2rB-8iwYt4GH2TTDJJb0txbaFVsArehkzmnTF1PmqSEfe_N8tu99CLp0Dyex4IDyEvGbxnTJoPACCYBq0ekRUruSiA8_IxWYEAXnDNf5yQZzHeArDSVOYpOeGMGVVpviLjZ1yCHejN0sQUbMJI546uuw5d8n-QbqxD-hXd3E8--XmifqLrAf_69HM7entG13SzTG73lFuubT9h8i4nYr6YcvZytL2fenqTlnb7nDzp7BDxxeE8Jd83H7-dXxRXXz5dnq-vClcKSAWzTlkttbGi1U3LnDJQSafAtZKjc0ILw6WTjbRaKItlqwBdJa2CthGmFKfk7b73Lsy_F4ypHn10OAx2wnmJda5jUjHQ_5W6lMIA11WWbx7I23kJ-dc7pHVpJDcZvdsjF-YYA3b1XfCjDduaQb3bqj5ule3rQ-HSjNge5f04Gbzag1829BiO4JD_BybvlsY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>848849529</pqid></control><display><type>article</type><title>Neural Substrates of Affective Face Recognition in Alexithymia: A Functional Magnetic Resonance Imaging Study</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><source>Karger E-Journals</source><creator>Lee, Byeong-Taek ; Lee, Hwa-Young ; Park, Sae-Ah ; Lim, Jin-Young ; Tae, Woo Suk ; Lee, Min-Soo ; Joe, Sook-Haeng ; Jung, In-Kwa ; Ham, Byung-Joo</creator><creatorcontrib>Lee, Byeong-Taek ; Lee, Hwa-Young ; Park, Sae-Ah ; Lim, Jin-Young ; Tae, Woo Suk ; Lee, Min-Soo ; Joe, Sook-Haeng ; Jung, In-Kwa ; Ham, Byung-Joo</creatorcontrib><description>Background: Alexithymia is a condition characterized by deficits in cognitive processing and the regulation of emotions. Several theories have been proposed for the underlying neurobiology, but the etiology of alexithymia remains unclear. Methods: Using functional magnetic resonance imaging, we investigated brain activation measured on the scale of alexithymia in 38 individuals who were presented with neutral, sad, or angry affective facial stimuli. Results: We found significant inverse correlations between the degree of alexithymia represented by the Korean version of the Toronto Alexithymia Scale (TAS-20K) and the intensity of the neural response to angry facial stimuli over neutral facial stimuli in the right caudate. This result was mainly due to the activations in factor 2 (difficulty describing feelings) in TAS-20K scale. Conclusions: The results suggest that functional impairments in the caudate of the fronto-striatal circuitry may play important roles in the pathophysiology of alexithymia.</description><identifier>ISSN: 0302-282X</identifier><identifier>EISSN: 1423-0224</identifier><identifier>DOI: 10.1159/000318086</identifier><identifier>PMID: 21196782</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Adult ; Affective Symptoms - physiopathology ; Brain - physiopathology ; Brain Mapping ; Cognitive ability ; Emotions ; Emotions - physiology ; Etiology ; Facial Expression ; Female ; Functional magnetic resonance imaging ; Humans ; Image Processing, Computer-Assisted ; Information processing ; Magnetic Resonance Imaging ; Nervous system ; Neuroimaging ; Original Paper ; Pattern recognition ; Recognition (Psychology) - physiology</subject><ispartof>Neuropsychobiology, 2011-01, Vol.63 (2), p.119-124</ispartof><rights>2010 S. Karger AG, Basel</rights><rights>2010 S. Karger AG, Basel.</rights><rights>Copyright (c) 2011 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-1ac6a8589a3d8bd1c69075c60cd52ecc383925c5b5a836ae4d60ec75a60db3943</citedby><cites>FETCH-LOGICAL-c430t-1ac6a8589a3d8bd1c69075c60cd52ecc383925c5b5a836ae4d60ec75a60db3943</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21196782$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Byeong-Taek</creatorcontrib><creatorcontrib>Lee, Hwa-Young</creatorcontrib><creatorcontrib>Park, Sae-Ah</creatorcontrib><creatorcontrib>Lim, Jin-Young</creatorcontrib><creatorcontrib>Tae, Woo Suk</creatorcontrib><creatorcontrib>Lee, Min-Soo</creatorcontrib><creatorcontrib>Joe, Sook-Haeng</creatorcontrib><creatorcontrib>Jung, In-Kwa</creatorcontrib><creatorcontrib>Ham, Byung-Joo</creatorcontrib><title>Neural Substrates of Affective Face Recognition in Alexithymia: A Functional Magnetic Resonance Imaging Study</title><title>Neuropsychobiology</title><addtitle>Neuropsychobiology</addtitle><description>Background: Alexithymia is a condition characterized by deficits in cognitive processing and the regulation of emotions. Several theories have been proposed for the underlying neurobiology, but the etiology of alexithymia remains unclear. Methods: Using functional magnetic resonance imaging, we investigated brain activation measured on the scale of alexithymia in 38 individuals who were presented with neutral, sad, or angry affective facial stimuli. Results: We found significant inverse correlations between the degree of alexithymia represented by the Korean version of the Toronto Alexithymia Scale (TAS-20K) and the intensity of the neural response to angry facial stimuli over neutral facial stimuli in the right caudate. This result was mainly due to the activations in factor 2 (difficulty describing feelings) in TAS-20K scale. Conclusions: The results suggest that functional impairments in the caudate of the fronto-striatal circuitry may play important roles in the pathophysiology of alexithymia.</description><subject>Adult</subject><subject>Affective Symptoms - physiopathology</subject><subject>Brain - physiopathology</subject><subject>Brain Mapping</subject><subject>Cognitive ability</subject><subject>Emotions</subject><subject>Emotions - physiology</subject><subject>Etiology</subject><subject>Facial Expression</subject><subject>Female</subject><subject>Functional magnetic resonance imaging</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Information processing</subject><subject>Magnetic Resonance Imaging</subject><subject>Nervous system</subject><subject>Neuroimaging</subject><subject>Original Paper</subject><subject>Pattern recognition</subject><subject>Recognition (Psychology) - physiology</subject><issn>0302-282X</issn><issn>1423-0224</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0c1rFDEYBvAgil2rB-8iwYt4GH2TTDJJb0txbaFVsArehkzmnTF1PmqSEfe_N8tu99CLp0Dyex4IDyEvGbxnTJoPACCYBq0ekRUruSiA8_IxWYEAXnDNf5yQZzHeArDSVOYpOeGMGVVpviLjZ1yCHejN0sQUbMJI546uuw5d8n-QbqxD-hXd3E8--XmifqLrAf_69HM7entG13SzTG73lFuubT9h8i4nYr6YcvZytL2fenqTlnb7nDzp7BDxxeE8Jd83H7-dXxRXXz5dnq-vClcKSAWzTlkttbGi1U3LnDJQSafAtZKjc0ILw6WTjbRaKItlqwBdJa2CthGmFKfk7b73Lsy_F4ypHn10OAx2wnmJda5jUjHQ_5W6lMIA11WWbx7I23kJ-dc7pHVpJDcZvdsjF-YYA3b1XfCjDduaQb3bqj5ule3rQ-HSjNge5f04Gbzag1829BiO4JD_BybvlsY</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>Lee, Byeong-Taek</creator><creator>Lee, Hwa-Young</creator><creator>Park, Sae-Ah</creator><creator>Lim, Jin-Young</creator><creator>Tae, Woo Suk</creator><creator>Lee, Min-Soo</creator><creator>Joe, Sook-Haeng</creator><creator>Jung, In-Kwa</creator><creator>Ham, Byung-Joo</creator><general>S. Karger AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>20110101</creationdate><title>Neural Substrates of Affective Face Recognition in Alexithymia: A Functional Magnetic Resonance Imaging Study</title><author>Lee, Byeong-Taek ; Lee, Hwa-Young ; Park, Sae-Ah ; Lim, Jin-Young ; Tae, Woo Suk ; Lee, Min-Soo ; Joe, Sook-Haeng ; Jung, In-Kwa ; Ham, Byung-Joo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-1ac6a8589a3d8bd1c69075c60cd52ecc383925c5b5a836ae4d60ec75a60db3943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Affective Symptoms - physiopathology</topic><topic>Brain - physiopathology</topic><topic>Brain Mapping</topic><topic>Cognitive ability</topic><topic>Emotions</topic><topic>Emotions - physiology</topic><topic>Etiology</topic><topic>Facial Expression</topic><topic>Female</topic><topic>Functional magnetic resonance imaging</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted</topic><topic>Information processing</topic><topic>Magnetic Resonance Imaging</topic><topic>Nervous system</topic><topic>Neuroimaging</topic><topic>Original Paper</topic><topic>Pattern recognition</topic><topic>Recognition (Psychology) - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Byeong-Taek</creatorcontrib><creatorcontrib>Lee, Hwa-Young</creatorcontrib><creatorcontrib>Park, Sae-Ah</creatorcontrib><creatorcontrib>Lim, Jin-Young</creatorcontrib><creatorcontrib>Tae, Woo Suk</creatorcontrib><creatorcontrib>Lee, Min-Soo</creatorcontrib><creatorcontrib>Joe, Sook-Haeng</creatorcontrib><creatorcontrib>Jung, In-Kwa</creatorcontrib><creatorcontrib>Ham, Byung-Joo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Psychology</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Neuropsychobiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Byeong-Taek</au><au>Lee, Hwa-Young</au><au>Park, Sae-Ah</au><au>Lim, Jin-Young</au><au>Tae, Woo Suk</au><au>Lee, Min-Soo</au><au>Joe, Sook-Haeng</au><au>Jung, In-Kwa</au><au>Ham, Byung-Joo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neural Substrates of Affective Face Recognition in Alexithymia: A Functional Magnetic Resonance Imaging Study</atitle><jtitle>Neuropsychobiology</jtitle><addtitle>Neuropsychobiology</addtitle><date>2011-01-01</date><risdate>2011</risdate><volume>63</volume><issue>2</issue><spage>119</spage><epage>124</epage><pages>119-124</pages><issn>0302-282X</issn><eissn>1423-0224</eissn><abstract>Background: Alexithymia is a condition characterized by deficits in cognitive processing and the regulation of emotions. Several theories have been proposed for the underlying neurobiology, but the etiology of alexithymia remains unclear. Methods: Using functional magnetic resonance imaging, we investigated brain activation measured on the scale of alexithymia in 38 individuals who were presented with neutral, sad, or angry affective facial stimuli. Results: We found significant inverse correlations between the degree of alexithymia represented by the Korean version of the Toronto Alexithymia Scale (TAS-20K) and the intensity of the neural response to angry facial stimuli over neutral facial stimuli in the right caudate. This result was mainly due to the activations in factor 2 (difficulty describing feelings) in TAS-20K scale. Conclusions: The results suggest that functional impairments in the caudate of the fronto-striatal circuitry may play important roles in the pathophysiology of alexithymia.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>21196782</pmid><doi>10.1159/000318086</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0302-282X |
| ispartof | Neuropsychobiology, 2011-01, Vol.63 (2), p.119-124 |
| issn | 0302-282X 1423-0224 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_907156108 |
| source | MEDLINE; Alma/SFX Local Collection; Karger E-Journals |
| subjects | Adult Affective Symptoms - physiopathology Brain - physiopathology Brain Mapping Cognitive ability Emotions Emotions - physiology Etiology Facial Expression Female Functional magnetic resonance imaging Humans Image Processing, Computer-Assisted Information processing Magnetic Resonance Imaging Nervous system Neuroimaging Original Paper Pattern recognition Recognition (Psychology) - physiology |
| title | Neural Substrates of Affective Face Recognition in Alexithymia: A Functional Magnetic Resonance Imaging Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T00%3A21%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Neural%20Substrates%20of%20Affective%20Face%20Recognition%20in%20Alexithymia:%20A%20Functional%20Magnetic%20Resonance%20Imaging%20Study&rft.jtitle=Neuropsychobiology&rft.au=Lee,%20Byeong-Taek&rft.date=2011-01-01&rft.volume=63&rft.issue=2&rft.spage=119&rft.epage=124&rft.pages=119-124&rft.issn=0302-282X&rft.eissn=1423-0224&rft_id=info:doi/10.1159/000318086&rft_dat=%3Cproquest_cross%3E907156108%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=848849529&rft_id=info:pmid/21196782&rfr_iscdi=true |