HLA-G expression in human embryonic stem cells and preimplantation embryos

Human leukocyte Ag-G, a tolerogenic molecule that acts on cells of both innate and adaptive immunity, plays an important role in tumor progression, transplantation, placentation, as well as the protection of the allogeneic fetus from the maternal immune system. We investigated HLA-G mRNA and protein...

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Veröffentlicht in:	The Journal of immunology (1950) 2011-02, Vol.186 (4), p.2663-2671
Hauptverfasser:	Verloes, An, Van de Velde, Hilde, LeMaoult, Joel, Mateizel, Ileana, Cauffman, Greet, Horn, Peter A, Carosella, Edgardo D, Devroey, Paul, De Waele, Marc, Rebmann, Vera, Vercammen, Martine
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, CD - metabolism Blastocyst Inner Cell Mass - cytology Blastocyst Inner Cell Mass - immunology Blastocyst Inner Cell Mass - metabolism Cell Line, Tumor Cells, Cultured Cleavage Stage, Ovum - cytology Cleavage Stage, Ovum - immunology Cleavage Stage, Ovum - metabolism Embryonic Stem Cells - immunology Embryonic Stem Cells - metabolism Gene Expression Regulation - immunology Histocompatibility Antigens Class I - biosynthesis Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - metabolism HLA Antigens - biosynthesis HLA Antigens - genetics HLA Antigens - metabolism HLA-G Antigens Humans Immune Tolerance - genetics Leukocyte Immunoglobulin-like Receptor B1 Oocytes - immunology Oocytes - metabolism Protein Binding - genetics Protein Binding - immunology Protein Isoforms - biosynthesis Protein Isoforms - genetics Protein Isoforms - metabolism Receptors, Immunologic - metabolism
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