Chronic Treatment with Imipramine and Lithium Increases Cell Proliferation in the Hippocampus in Adrenocorticotropic Hormone-Treated Rats

Adult hippocampal neurogenesis is reported to change in animal models of depression and antidepressants. We have used the mitotic marker 5-bromo-2′-deoxyyridine to address the effects of imipramine and lithium on cell proliferation and survival following chronic treatment with adrenocorticotropic ho...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2011/01/01, Vol.34(1), pp.77-81
Hauptverfasser:	Kitamura, Yoshihisa, Doi, Maho, Kuwatsuka, Keiko, Onoue, Yuka, Miyazaki, Ikuko, Shinomiya, Kazuaki, Koyama, Toshihiro, Sendo, Toshiaki, Kawasaki, Hiromu, Asanuma, Masato, Gomita, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	5-bromo-2′-deoxyyridine Adrenocorticotropic hormone Adrenocorticotropic Hormone - pharmacology Animal models Animals Antidepressants Antidepressive Agents, Tricyclic - pharmacology Antimanic Agents - pharmacology Cell proliferation Cell Proliferation - drug effects Cell survival Dentate gyrus Depression Hippocampus Hippocampus - cytology imipramine Imipramine - pharmacology Lithium Lithium - pharmacology Male Neurogenesis Neurogenesis - drug effects Neurons - cytology Neurons - drug effects Rats Rats, Wistar
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