Significant association of high-risk human papillomavirus (HPV) but not of p53 polymorphisms with oral squamous cell carcinomas in Malaysia

Purpose The purpose of this study was to evaluate the role of HPV and p53 polymorphisms in oral squamous cell carcinomas (OSCC) affecting Malaysian population. Methods We analysed frozen samples from 105 OSCC as well as 105 oral specimens derived from healthy individuals. PCR assays targeting two re...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cancer research and clinical oncology 2011-02, Vol.137 (2), p.311-320
Hauptverfasser:	Saini, Rajan, Tang, Thean-Hock, Zain, Rosnah Binti, Cheong, Sok Ching, Musa, Kamarul Imran, Saini, Deepti, Ismail, Abdul Rashid, Abraham, Mannil Thomas, Mustafa, Wan Mahadzir Wan, Santhanam, Jacinta
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Alphapapillomavirus - genetics Alphapapillomavirus - isolation & purification Antineoplastic agents Arginine Biological and medical sciences Cancer Research Carcinoma, Squamous Cell - ethnology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - virology Case-Control Studies Codons Demography DNA, Viral - isolation & purification Female Hematology High-risk HPV Human papillomavirus Humans Infection Infectious diseases Internal Medicine Logistic Models Malaysia - epidemiology Male Medical sciences Medicine Medicine & Public Health Middle Aged Mouth Neoplasms - ethnology Mouth Neoplasms - genetics Mouth Neoplasms - virology Odds Ratio Oncology Oral cancer Oral squamous cell carcinoma Original Paper Otorhinolaryngology. Stomatology p53 polymorphism p53 protein Papillomavirus Infections - complications Papillomavirus Infections - ethnology Papillomavirus Infections - virology Pharmacology. Drug treatments Polymerase Chain Reaction Polymorphism Polymorphism, Single Nucleotide Population genetics Proline Races Retrospective Studies Risk Assessment Risk Factors Risk groups Tumor Suppressor Protein p53 - genetics Tumor Virus Infections - complications Tumor Virus Infections - ethnology Tumor Virus Infections - virology Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Viral diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!