Antinuclear autoantibodies are more prevalent in COPD in association with low body mass index but not with smoking history

BackgroundChronic obstructive pulmonary disease (COPD) is associated with a higher prevalence of antinuclear autoantibodies (ANAs). However, a significant subgroup of patients is ANA negative. It remains to be determined which patient groups carry autoantibodies.MethodsThe association of smoking beh...

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Veröffentlicht in:	Thorax 2011-02, Vol.66 (2), p.101-107
Hauptverfasser:	Bonarius, H P J, Brandsma, C A, Kerstjens, H A M, Koerts, J A, Kerkhof, M, Nizankowska-Mogilnicka, E, Roozendaal, C, Postma, D S, Timens, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Aged Antibodies, Antineutrophil Cytoplasmic - blood Antibodies, Antinuclear - blood Antigens auto-antibodies Autoimmune diseases autoimmunity B-cells B-Lymphocytes - immunology Biological and medical sciences Body Mass Index Cardiology. Vascular system Case-Control Studies Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease, asthma COPD mechanisms COPD pathology Diagnostic tests Emphysema Female Forced Expiratory Volume - immunology Gender Genotype & phenotype Health risk assessment Humans Immunoglobulin Heavy Chains - immunology Immunoglobulins Laboratories Lung - immunology Lung diseases Male Medical sciences Middle Aged Mortality Patients Pneumology Population Pulmonary Disease, Chronic Obstructive - immunology Pulmonary Disease, Chronic Obstructive - physiopathology Sex Factors Smoking Smoking - immunology Smooth muscle Studies Tobacco, tobacco smoking Toxicology Vital Capacity - immunology
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