Effects of Antioxidants of Different Nature on Functions of Tissue—Blood Barriers of the Neuroendocrine Center of Wistar White Rats of Both Sexes

Effects of Antioxidants of Different Nature on Functions of Tissue—Blood Barriers of the Neuroendocrine Center of Wistar White Rats of Both Sexes

Effects of natural (α-tocopherol) and synthetic (ionol) antioxidants on permeability of tissue--blood barriers of the hypothalamus-pituitary system to an alien (the dye neutral red) and physiologically adequate agent (^sup 3^H-thymidine) were studied in male and female Wistar rats. The antioxidants...

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Veröffentlicht in:Journal of evolutionary biochemistry and physiology 2005-11, Vol.41 (6), p.671-676
Hauptverfasser: Kotel'nikov, A V, Teplyi, D L, Balybin, E S
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Antioxidants
Permeability
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container_title Journal of evolutionary biochemistry and physiology
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creator Kotel'nikov, A V
Teplyi, D L
Balybin, E S
description Effects of natural (α-tocopherol) and synthetic (ionol) antioxidants on permeability of tissue--blood barriers of the hypothalamus-pituitary system to an alien (the dye neutral red) and physiologically adequate agent (^sup 3^H-thymidine) were studied in male and female Wistar rats. The antioxidants were established to enhance the protective function of the tissue--blood barriers, especially in females. The permeability to ^sup 3^H-thymidine in hypothalamus decreased only in males and only after effect of α-tocopherol, whereas in pituitary, in animals of both sexes and especially after action of the bioantioxidant.[PUBLICATION ABSTRACT]
doi_str_mv 10.1007/s10893-006-0009-y
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subjects Antioxidants
Permeability
title Effects of Antioxidants of Different Nature on Functions of Tissue—Blood Barriers of the Neuroendocrine Center of Wistar White Rats of Both Sexes
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