Sam68 interacts with IRS1

Sam68 (Src associated in mitosis) is a RNA binding protein that links cellular signaling to RNA processing. In previous studies we found that insulin promotes Sam68 relocalization in the cytoplasm allowing Sam68 to associate with p85PI3K, Grb2, GAP and probably the insulin receptor (IR), modulating...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical pharmacology 2012, Vol.83 (1), p.78-87
Hauptverfasser:	Quintana-Portillo, R., Canfrán-Duque, A., Issad, T., Sánchez-Margalet, V., González-Yanes, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - metabolism Antigens, CD - metabolism Biological and medical sciences BRET DNA-Binding Proteins - metabolism HEK293 Cells Humans Insulin - metabolism Insulin - physiology Insulin receptor Insulin Receptor Substrate Proteins - metabolism IRS1 Medical sciences Pharmacology. Drug treatments Protein Binding - physiology Protein Interaction Domains and Motifs - physiology Receptor, Insulin - metabolism RNA-Binding Proteins - metabolism Sam68 Substrate Specificity - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!