Estrogen dependent signaling in reproductive tissues – A role for estrogen receptors and estrogen related receptors

► Estrogens regulate the reproductive and cardiovascular systems, the skeleton and the brain. ► Estrogen receptor (ERα, β) genes are subject to alternative splicing. ► Ratios of ER subtypes/variants in cells determines the impact of estrogens on tissue function. ► ERα, β, and ERβ variants, have uniq...

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Veröffentlicht in:	Molecular and cellular endocrinology 2012-01, Vol.348 (2), p.361-372
Hauptverfasser:	Gibson, Douglas A., Saunders, Philippa T.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological effects Cancer Estrogen receptor estrogen receptors Estrogen related receptor Estrogens Fertility Gene Expression Regulation, Developmental Genitalia - cytology Genitalia - growth & development Genitalia - metabolism Humans neoplasms ontogeny Protein Isoforms - chemistry Protein Isoforms - metabolism Protein Isoforms - physiology Protein Structure, Tertiary Receptors, Estrogen - chemistry Receptors, Estrogen - metabolism Receptors, Estrogen - physiology Signal Transduction tissues
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