Chronic pulmonary diseases are independent risk factors for complications after radical nephrectomy
Aim We aimed to identify the prognostic factors and the new parameters such as Charlson’s comorbidity index (CCI) that might predict postoperative complication rates in a radical nephrectomy cohort. We also evaluated the correlation of CCI with the Clavien postoperative complication scale (CPCS). Ma...
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| Veröffentlicht in: | International urology and nephrology 2011-12, Vol.43 (4), p.1025-1031 |
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| container_title | International urology and nephrology |
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| creator | Tokgöz, Hüsnü Akduman, Bülent Ünal, İlker Erol, Bülent Akyürek, Ersöz Mungan, Necmettin Aydin |
| description | Aim
We aimed to identify the prognostic factors and the new parameters such as Charlson’s comorbidity index (CCI) that might predict postoperative complication rates in a radical nephrectomy cohort. We also evaluated the correlation of CCI with the Clavien postoperative complication scale (CPCS).
Materials and methods
Perioperative characteristics of 47 patients undergoing radical nephrectomy were recorded. Following items were assessed: preoperative patient characteristics including age, gender, CCI, American Society of Anesthesiologists (ASA) physical status classification system category, renal and hepatic functions, type of nephrectomy incision, operative time, clinical stage and histopathological subtype of the tumor, and preoperative co-morbid conditions including diabetes mellitus, hypertension, chronic pulmonary disease, peptic ulcers, renal and hepatic dysfunction. Postoperative complications were defined as death, wound infection, pneumonia, atelectasis, pulmonary emboli, anemia, sepsis, cardiac arrhythmia, myocardial infarction, and deep vein thrombosis. In addition, postoperative complications were also graded according to the CPCS and accepted as those occurring within 30 days.
Results
Preoperative chronic pulmonary diseases were found to be significant risk factors for the development of postoperative complications. Age adjusted odds ratio was 7.112 for chronic pulmonary disease. The mean CCI in patients who did not develop any postoperative complication was 4.49 ± 1.95, whereas it was 5.75 ± 2.60 for patients who developed postoperative complications (
P
= 0.138). In Spearman correlation analysis, CCI value was found to be significantly correlated with CPCS grade (
P
= 0.011, rho value = 0.366).
Conclusion
Presence of chronic pulmonary disease is a strong predictor of postoperative complications after radical nephrectomy. Patients with higher preoperative CCI scores may have higher postoperative CPCS grades. Additional studies are warranted. |
| doi_str_mv | 10.1007/s11255-011-9957-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_906556176</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>906556176</sourcerecordid><originalsourceid>FETCH-LOGICAL-c370t-f5e41f429163258561ab89c5e15705f51be7d534b7bdce47a5c918c8efe2d70c3</originalsourceid><addsrcrecordid>eNp1kMFO3DAQhi1EBQvtA3CpLC6cQmecOE6OaAUFCYkLPVuOM4bQxA52cuDt69XSVkLi4pE83_z2fIydIVwigPqREIWUBSAWbStVIQ7YBqUqCyGb6pBtoAQssBblMTtJ6QUA2gbgiB0LlFhXqt4wu32OwQ-Wz-s4BW_iG--HRCZR4iYSH3xPM-XDLzwO6Td3xi4hJu5C5DZM8zhYswzBZ9wtFHk0fb4Zuaf5OVJmp7ev7IszY6Jv7_WU_bq5ftzeFvcPP--2V_eFLRUshZNUoatEi3WZF5A1mq5praS8EkgnsSPVy7LqVNdbqpSRtsXGNuRI9Apsecou9rlzDK8rpUVPQ7I0jsZTWJNuoZY5VdWZPP9AvoQ1-vy5HYRQ1VJkCPeQjSGlSE7PcZiyIY2gd_713r_O_vXOv97NfH8PXruJ-n8Tf4VnQOyBlFv-ieL_lz9P_QOCeZFm</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>906104652</pqid></control><display><type>article</type><title>Chronic pulmonary diseases are independent risk factors for complications after radical nephrectomy</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Tokgöz, Hüsnü ; Akduman, Bülent ; Ünal, İlker ; Erol, Bülent ; Akyürek, Ersöz ; Mungan, Necmettin Aydin</creator><creatorcontrib>Tokgöz, Hüsnü ; Akduman, Bülent ; Ünal, İlker ; Erol, Bülent ; Akyürek, Ersöz ; Mungan, Necmettin Aydin</creatorcontrib><description>Aim
We aimed to identify the prognostic factors and the new parameters such as Charlson’s comorbidity index (CCI) that might predict postoperative complication rates in a radical nephrectomy cohort. We also evaluated the correlation of CCI with the Clavien postoperative complication scale (CPCS).
Materials and methods
Perioperative characteristics of 47 patients undergoing radical nephrectomy were recorded. Following items were assessed: preoperative patient characteristics including age, gender, CCI, American Society of Anesthesiologists (ASA) physical status classification system category, renal and hepatic functions, type of nephrectomy incision, operative time, clinical stage and histopathological subtype of the tumor, and preoperative co-morbid conditions including diabetes mellitus, hypertension, chronic pulmonary disease, peptic ulcers, renal and hepatic dysfunction. Postoperative complications were defined as death, wound infection, pneumonia, atelectasis, pulmonary emboli, anemia, sepsis, cardiac arrhythmia, myocardial infarction, and deep vein thrombosis. In addition, postoperative complications were also graded according to the CPCS and accepted as those occurring within 30 days.
Results
Preoperative chronic pulmonary diseases were found to be significant risk factors for the development of postoperative complications. Age adjusted odds ratio was 7.112 for chronic pulmonary disease. The mean CCI in patients who did not develop any postoperative complication was 4.49 ± 1.95, whereas it was 5.75 ± 2.60 for patients who developed postoperative complications (
P
= 0.138). In Spearman correlation analysis, CCI value was found to be significantly correlated with CPCS grade (
P
= 0.011, rho value = 0.366).
Conclusion
Presence of chronic pulmonary disease is a strong predictor of postoperative complications after radical nephrectomy. Patients with higher preoperative CCI scores may have higher postoperative CPCS grades. Additional studies are warranted.</description><identifier>ISSN: 0301-1623</identifier><identifier>EISSN: 1573-2584</identifier><identifier>DOI: 10.1007/s11255-011-9957-2</identifier><identifier>PMID: 21516476</identifier><identifier>CODEN: IURNAE</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Carcinoma, Renal Cell - pathology ; Carcinoma, Renal Cell - surgery ; Chronic Disease ; Decision Support Techniques ; Female ; Humans ; Kidney Neoplasms - pathology ; Kidney Neoplasms - surgery ; Lung Diseases - complications ; Lung Diseases - etiology ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multivariate Analysis ; Nephrectomy - adverse effects ; Nephrology ; Odds Ratio ; Postoperative Complications - etiology ; Prognosis ; Statistics, Nonparametric ; Urology ; Urology – Original Paper</subject><ispartof>International urology and nephrology, 2011-12, Vol.43 (4), p.1025-1031</ispartof><rights>Springer Science+Business Media, B.V. 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-f5e41f429163258561ab89c5e15705f51be7d534b7bdce47a5c918c8efe2d70c3</citedby><cites>FETCH-LOGICAL-c370t-f5e41f429163258561ab89c5e15705f51be7d534b7bdce47a5c918c8efe2d70c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11255-011-9957-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11255-011-9957-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21516476$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tokgöz, Hüsnü</creatorcontrib><creatorcontrib>Akduman, Bülent</creatorcontrib><creatorcontrib>Ünal, İlker</creatorcontrib><creatorcontrib>Erol, Bülent</creatorcontrib><creatorcontrib>Akyürek, Ersöz</creatorcontrib><creatorcontrib>Mungan, Necmettin Aydin</creatorcontrib><title>Chronic pulmonary diseases are independent risk factors for complications after radical nephrectomy</title><title>International urology and nephrology</title><addtitle>Int Urol Nephrol</addtitle><addtitle>Int Urol Nephrol</addtitle><description>Aim
We aimed to identify the prognostic factors and the new parameters such as Charlson’s comorbidity index (CCI) that might predict postoperative complication rates in a radical nephrectomy cohort. We also evaluated the correlation of CCI with the Clavien postoperative complication scale (CPCS).
Materials and methods
Perioperative characteristics of 47 patients undergoing radical nephrectomy were recorded. Following items were assessed: preoperative patient characteristics including age, gender, CCI, American Society of Anesthesiologists (ASA) physical status classification system category, renal and hepatic functions, type of nephrectomy incision, operative time, clinical stage and histopathological subtype of the tumor, and preoperative co-morbid conditions including diabetes mellitus, hypertension, chronic pulmonary disease, peptic ulcers, renal and hepatic dysfunction. Postoperative complications were defined as death, wound infection, pneumonia, atelectasis, pulmonary emboli, anemia, sepsis, cardiac arrhythmia, myocardial infarction, and deep vein thrombosis. In addition, postoperative complications were also graded according to the CPCS and accepted as those occurring within 30 days.
Results
Preoperative chronic pulmonary diseases were found to be significant risk factors for the development of postoperative complications. Age adjusted odds ratio was 7.112 for chronic pulmonary disease. The mean CCI in patients who did not develop any postoperative complication was 4.49 ± 1.95, whereas it was 5.75 ± 2.60 for patients who developed postoperative complications (
P
= 0.138). In Spearman correlation analysis, CCI value was found to be significantly correlated with CPCS grade (
P
= 0.011, rho value = 0.366).
Conclusion
Presence of chronic pulmonary disease is a strong predictor of postoperative complications after radical nephrectomy. Patients with higher preoperative CCI scores may have higher postoperative CPCS grades. Additional studies are warranted.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Carcinoma, Renal Cell - pathology</subject><subject>Carcinoma, Renal Cell - surgery</subject><subject>Chronic Disease</subject><subject>Decision Support Techniques</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Neoplasms - pathology</subject><subject>Kidney Neoplasms - surgery</subject><subject>Lung Diseases - complications</subject><subject>Lung Diseases - etiology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Nephrectomy - adverse effects</subject><subject>Nephrology</subject><subject>Odds Ratio</subject><subject>Postoperative Complications - etiology</subject><subject>Prognosis</subject><subject>Statistics, Nonparametric</subject><subject>Urology</subject><subject>Urology – Original Paper</subject><issn>0301-1623</issn><issn>1573-2584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kMFO3DAQhi1EBQvtA3CpLC6cQmecOE6OaAUFCYkLPVuOM4bQxA52cuDt69XSVkLi4pE83_z2fIydIVwigPqREIWUBSAWbStVIQ7YBqUqCyGb6pBtoAQssBblMTtJ6QUA2gbgiB0LlFhXqt4wu32OwQ-Wz-s4BW_iG--HRCZR4iYSH3xPM-XDLzwO6Td3xi4hJu5C5DZM8zhYswzBZ9wtFHk0fb4Zuaf5OVJmp7ev7IszY6Jv7_WU_bq5ftzeFvcPP--2V_eFLRUshZNUoatEi3WZF5A1mq5praS8EkgnsSPVy7LqVNdbqpSRtsXGNuRI9Apsecou9rlzDK8rpUVPQ7I0jsZTWJNuoZY5VdWZPP9AvoQ1-vy5HYRQ1VJkCPeQjSGlSE7PcZiyIY2gd_713r_O_vXOv97NfH8PXruJ-n8Tf4VnQOyBlFv-ieL_lz9P_QOCeZFm</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Tokgöz, Hüsnü</creator><creator>Akduman, Bülent</creator><creator>Ünal, İlker</creator><creator>Erol, Bülent</creator><creator>Akyürek, Ersöz</creator><creator>Mungan, Necmettin Aydin</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Chronic pulmonary diseases are independent risk factors for complications after radical nephrectomy</title><author>Tokgöz, Hüsnü ; Akduman, Bülent ; Ünal, İlker ; Erol, Bülent ; Akyürek, Ersöz ; Mungan, Necmettin Aydin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c370t-f5e41f429163258561ab89c5e15705f51be7d534b7bdce47a5c918c8efe2d70c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Carcinoma, Renal Cell - pathology</topic><topic>Carcinoma, Renal Cell - surgery</topic><topic>Chronic Disease</topic><topic>Decision Support Techniques</topic><topic>Female</topic><topic>Humans</topic><topic>Kidney Neoplasms - pathology</topic><topic>Kidney Neoplasms - surgery</topic><topic>Lung Diseases - complications</topic><topic>Lung Diseases - etiology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Nephrectomy - adverse effects</topic><topic>Nephrology</topic><topic>Odds Ratio</topic><topic>Postoperative Complications - etiology</topic><topic>Prognosis</topic><topic>Statistics, Nonparametric</topic><topic>Urology</topic><topic>Urology – Original Paper</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tokgöz, Hüsnü</creatorcontrib><creatorcontrib>Akduman, Bülent</creatorcontrib><creatorcontrib>Ünal, İlker</creatorcontrib><creatorcontrib>Erol, Bülent</creatorcontrib><creatorcontrib>Akyürek, Ersöz</creatorcontrib><creatorcontrib>Mungan, Necmettin Aydin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>International urology and nephrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tokgöz, Hüsnü</au><au>Akduman, Bülent</au><au>Ünal, İlker</au><au>Erol, Bülent</au><au>Akyürek, Ersöz</au><au>Mungan, Necmettin Aydin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Chronic pulmonary diseases are independent risk factors for complications after radical nephrectomy</atitle><jtitle>International urology and nephrology</jtitle><stitle>Int Urol Nephrol</stitle><addtitle>Int Urol Nephrol</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>43</volume><issue>4</issue><spage>1025</spage><epage>1031</epage><pages>1025-1031</pages><issn>0301-1623</issn><eissn>1573-2584</eissn><coden>IURNAE</coden><abstract>Aim
We aimed to identify the prognostic factors and the new parameters such as Charlson’s comorbidity index (CCI) that might predict postoperative complication rates in a radical nephrectomy cohort. We also evaluated the correlation of CCI with the Clavien postoperative complication scale (CPCS).
Materials and methods
Perioperative characteristics of 47 patients undergoing radical nephrectomy were recorded. Following items were assessed: preoperative patient characteristics including age, gender, CCI, American Society of Anesthesiologists (ASA) physical status classification system category, renal and hepatic functions, type of nephrectomy incision, operative time, clinical stage and histopathological subtype of the tumor, and preoperative co-morbid conditions including diabetes mellitus, hypertension, chronic pulmonary disease, peptic ulcers, renal and hepatic dysfunction. Postoperative complications were defined as death, wound infection, pneumonia, atelectasis, pulmonary emboli, anemia, sepsis, cardiac arrhythmia, myocardial infarction, and deep vein thrombosis. In addition, postoperative complications were also graded according to the CPCS and accepted as those occurring within 30 days.
Results
Preoperative chronic pulmonary diseases were found to be significant risk factors for the development of postoperative complications. Age adjusted odds ratio was 7.112 for chronic pulmonary disease. The mean CCI in patients who did not develop any postoperative complication was 4.49 ± 1.95, whereas it was 5.75 ± 2.60 for patients who developed postoperative complications (
P
= 0.138). In Spearman correlation analysis, CCI value was found to be significantly correlated with CPCS grade (
P
= 0.011, rho value = 0.366).
Conclusion
Presence of chronic pulmonary disease is a strong predictor of postoperative complications after radical nephrectomy. Patients with higher preoperative CCI scores may have higher postoperative CPCS grades. Additional studies are warranted.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>21516476</pmid><doi>10.1007/s11255-011-9957-2</doi><tpages>7</tpages></addata></record> |
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| ispartof | International urology and nephrology, 2011-12, Vol.43 (4), p.1025-1031 |
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| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Adult Aged Aged, 80 and over Carcinoma, Renal Cell - pathology Carcinoma, Renal Cell - surgery Chronic Disease Decision Support Techniques Female Humans Kidney Neoplasms - pathology Kidney Neoplasms - surgery Lung Diseases - complications Lung Diseases - etiology Male Medicine Medicine & Public Health Middle Aged Multivariate Analysis Nephrectomy - adverse effects Nephrology Odds Ratio Postoperative Complications - etiology Prognosis Statistics, Nonparametric Urology Urology – Original Paper |
| title | Chronic pulmonary diseases are independent risk factors for complications after radical nephrectomy |
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