Long-Term Follow-Up After Fractional Flow Reserve–Guided Treatment Strategy in Patients With an Isolated Proximal Left Anterior Descending Coronary Artery Stenosis

Long-Term Follow-Up After Fractional Flow Reserve–Guided Treatment Strategy in Patients With an Isolated Proximal Left Anterior Descending Coronary Artery Stenosis Olivier Muller, Fabio Mangiacapra, Argyrios Ntalianis, Katia M. C. Verhamme, Catalina Trana, Michalis Hamilos, Jozef Bartunek, Marc Vand...

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Veröffentlicht in:	JACC. Cardiovascular interventions 2011-11, Vol.4 (11), p.1175-1182
Hauptverfasser:	Muller, Olivier, MD, PhD, Mangiacapra, Fabio, MD, Ntalianis, Argyrios, MD, PhD, Verhamme, Katia M.C., MD, PhD, Trana, Catalina, MD, Hamilos, Michalis, MD, PhD, Bartunek, Jozef, MD, PhD, Vanderheyden, Marc, MD, Wyffels, Eric, MD, Heyndrickx, Guy R., MD, PhD, van Rooij, Frank J.A., DSc, Witteman, Jacqueline C.M., MSc, PhD, Hofman, Albert, MD, PhD, Wijns, William, MD, PhD, Barbato, Emanuele, MD, PhD, De Bruyne, Bernard, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angioplasty, Balloon, Coronary - adverse effects Angioplasty, Balloon, Coronary - mortality Belgium Cardiac Catheterization Cardiovascular Cardiovascular Agents - therapeutic use Chi-Square Distribution Coronary Angiography Coronary Artery Bypass - adverse effects Coronary Artery Bypass - mortality Coronary Stenosis - diagnosis Coronary Stenosis - mortality Coronary Stenosis - physiopathology Coronary Stenosis - therapy Disease-Free Survival Female fractional flow reserve Fractional Flow Reserve, Myocardial Hemodynamics Humans Kaplan-Meier Estimate Male Middle Aged Myocardial Infarction - etiology myocardial ischemia Netherlands Patient Selection Predictive Value of Tests Proportional Hazards Models proximal left anterior descending coronary artery Registries Risk Assessment Risk Factors Severity of Illness Index Survival Rate Time Factors Treatment Outcome
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Zusammenfassung:	Long-Term Follow-Up After Fractional Flow Reserve–Guided Treatment Strategy in Patients With an Isolated Proximal Left Anterior Descending Coronary Artery Stenosis Olivier Muller, Fabio Mangiacapra, Argyrios Ntalianis, Katia M. C. Verhamme, Catalina Trana, Michalis Hamilos, Jozef Bartunek, Marc Vanderheyden, Eric Wyffels, Guy R. Heyndrickx, Frank J. A. van Rooij, Jacqueline C. M. Witteman, Albert Hofman, William Wijns, Emanuele Barbato, Bernard De Bruyne The aim of the study was to assess the long-term clinical outcome of 730 patients with an angiographically intermediate left anterior descending coronary artery (LAD) stenosis in whom the revascularization strategy was based on fractional flow reserve (FFR). The 5-year survival estimate was 92.9% in the medical group (FFR ≥0.8) versus 89.6% in the controls (age- and sex-matched reference population, p = 0.74) versus 87.4% in the revascularization group (FFR
ISSN:	1936-8798 1876-7605
DOI:	10.1016/j.jcin.2011.09.007