Quaternary association in beta-prism I2 fold plant lectins: insights from X-ray crystallography, modelling and molecular dynamics

Dimeric banana lectin and calsepa, tetrameric artocarpin and octameric heltuba are mannose-specific beta-prism I fold lectins of nearly the same tertiary structure. MD simulations on individual subunits and the oligomers provide insights into the changes in the structure brought about in the protome...

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Veröffentlicht in:	Journal of biosciences 2011-12, Vol.36 (5), p.793-808
Hauptverfasser:	Sharma, Alok, Vijayan, Mamannamana
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Artocarpus Calystegia Crystallography, X-Ray Helianthus Hydrogen Bonding Models, Molecular Molecular Dynamics Simulation Molecular Sequence Data Multiprotein Complexes Musa Plant Lectins - chemistry Protein Binding Protein Multimerization Protein Structure, Quaternary Protein Structure, Secondary Structural Homology, Protein Thermodynamics
Online-Zugang:	Volltext
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