Dendritic Spine Plasticity in Gonadatropin-Releasing Hormone (GnRH) Neurons Activated at the Time of the Preovulatory Surge

GnRH neuron activity is dependent on gonadal steroid hormone feedback. Altered synaptic input may be one mechanism by which steroids modify GnRH neuron activity. In other neuronal populations, steroid hormones have been shown to elicit profound effects on dendritic spine density, a measure of excita...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2011-12, Vol.152 (12), p.4906-4914
Hauptverfasser:	Chan, Heidi, Prescott, Melanie, Ong, ZhiYi, Herde, Michel K, Herbison, Allan E, Campbell, Rebecca E
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Animals Benzoates Biological and medical sciences Body weight Dendritic plasticity Dendritic spines Dendritic Spines - drug effects Dendritic Spines - ultrastructure Dendritic structure Density Estradiol - administration & dosage Estradiol - pharmacology Feedback Feedback, Physiological Female Females Fluorescence Fundamental and applied biological sciences. Psychology Gonadotropin-Releasing Hormone Green fluorescent protein Green Fluorescent Proteins Hormones Immunofluorescence Labels Luteinizing hormone Mice Microscopy, Confocal Neurons Neurons - metabolism Neurons - ultrastructure Ovariectomy Ovulation Population studies Positive feedback Sex hormones Spine Steroid hormones Steroids Synaptic density Synaptic plasticity Time dependence Vertebrates: endocrinology
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