Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation

Acetoacetyl-CoA thiolase (EC 2.3.1.9), also called thiolase II, condenses two molecules of acetyl-CoA to give acetoacetyl-CoA. This is the first enzymatic step in the biosynthesis of isoprenoids via mevalonate (MVA). In this work, thiolase II from alfalfa (MsAACT1) was identified and cloned. The enz...

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Veröffentlicht in:	Journal of experimental botany 2011-11, Vol.62 (15), p.5699-5711
Hauptverfasser:	Soto, Gabriela, Stritzler, Margarita, Lisi, Christian, Alleva, Karina, Pagano, María Elba, Ardila, Fernando, Mozzicafreddo, Matteo, Cuccioloni, Massimiliano, Angeletti, Mauro, Ayub, Nicolás Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA C-Acetyltransferase - genetics Acetyl-CoA C-Acetyltransferase - metabolism Alfalfa Antioxidants Biological and medical sciences Biosynthesis Enzymes Fundamental and applied biological sciences. Psychology Medicago sativa - drug effects Medicago sativa - genetics Medicago sativa - metabolism Mevalonic Acid - metabolism Plant Leaves - drug effects Plant Leaves - genetics Plant Leaves - metabolism Plant physiology and development Plant Proteins - genetics Plant Proteins - metabolism Plant roots Plant Roots - drug effects Plant Roots - genetics Plant Roots - metabolism Plants Plants, Genetically Modified - drug effects Plants, Genetically Modified - genetics Plants, Genetically Modified - metabolism Pravastatin - pharmacology Pseudomonas Real-Time Polymerase Chain Reaction RESEARCH PAPER Salinity Signal Transduction - drug effects Signal Transduction - genetics Squalene Squalene - metabolism Terpenoids
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