Large-Scale Candidate Gene Analysis in Whites and African Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation: The National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) Project

The genetic background of atrial fibrillation (AF) in whites and African Americans is largely unknown. Genes in cardiovascular pathways have not been systematically investigated. We examined a panel of approximately 50,000 common single-nucleotide polymorphisms (SNPs) in 2095 cardiovascular candidat...

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Veröffentlicht in:	Circulation. Cardiovascular genetics 2011-10, Vol.4 (5), p.557-564
Hauptverfasser:	SCHNABEL, Renate B, KERR, Kathleen F, LUNETTA, Kathryn L, MEHRA, Reena, LEVY, Daniel, FOX, Ervin R, ARKING, Dan E, MOSLEY, Thomas H, MÜLLER-NURASYID, Martina, YOUNG, Taylor R, WICHMANN, H.-Erich, SESHADRI, Sudha, LUBITZ, Steven A, FARLOW, Deborah N, ROTTER, Jerome I, SOLIMAN, Elsayed Z, GLAZER, Nicole L, WILSON, James G, BRETELER, Monique M. B, SOTOODEHNIA, Nona, NEWTON-CHEH, Christonher, KÄÄB, Stefan, ELLINOR, Patrick T, ALKYLBEKOVA, Ermeg L, ALONSO, Alvaro, BENJAMIN, Emelia J, HECKBERT, Susan R, MARCUS, Gregory M, SINNER, Moritz F, MAGNANI, Jared W, WOLF, Philip A, DEO, Rajat, LLOYD-JONES, Donald M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Atrial Fibrillation - genetics Biological and medical sciences Black or African American - genetics Cardiac dysrhythmias Cardiology. Vascular system Chromosome aberrations Chromosomes, Human, Pair 4 Cohort Studies Female Heart Humans Male Medical genetics Medical sciences Middle Aged National Heart, Lung, and Blood Institute (U.S.) Neurology Polymorphism, Single Nucleotide Receptors, Interleukin-6 - genetics Risk Factors Stroke - epidemiology United States Vascular diseases and vascular malformations of the nervous system White People - genetics
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