Down-regulation of MiR-206 Promotes Proliferation and Invasion of Laryngeal Cancer by Regulating VEGF Expression

MicroRNAs (miRNA) are a class of small noncoding RNAs that regulate the expression of their target genes. The aim of the present study was to explore the effects of miR-206 on laryngeal suamous cell carcinoma (LSCC) cells. The expression level of miR-206 was quantified by qRT-PCR in primary LSCC tis...

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Veröffentlicht in:	Anticancer research 2011-11, Vol.31 (11), p.3859-3863
Hauptverfasser:	Zhang, Tianhong, Liu, Ming, Wang, Chunrui, Lin, Chao, Sun, Yanan, Jin, Dejun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biological and medical sciences Blotting, Western Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Cell Adhesion Cell Line, Tumor Cell Movement Cell Proliferation Down-Regulation Female Flow Cytometry Gene Expression Regulation, Neoplastic Humans Immunoenzyme Techniques Laryngeal Neoplasms - genetics Laryngeal Neoplasms - metabolism Laryngeal Neoplasms - pathology Lymphatic Metastasis Male Medical sciences Mice Mice, Inbred BALB C MicroRNAs - physiology Middle Aged Neoplasm Invasiveness Otorhinolaryngology. Stomatology Real-Time Polymerase Chain Reaction RNA, Messenger - genetics Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Vascular Endothelial Growth Factor A - antagonists & inhibitors Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - metabolism
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