Tooth injury increases expression of the cold sensitive TRP channel TRPA1 in trigeminal neurons

Abstract Objective Transient receptor potential (TRP) channels, a family of structurally related proteins have been implicated in the sensation of pain and hyperalgesia caused by exogenous and endogenous agonists, as well as touch, pH, and temperature. The objective of this study was to determine th...

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Veröffentlicht in:	Archives of oral biology 2011-12, Vol.56 (12), p.1604-1609
Hauptverfasser:	Haas, Eric T, Rowland, Kevin, Gautam, Medha
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Blotting, Western Dental pulp Dentistry Humans Hyperalgesia - metabolism Hyperalgesia - physiopathology Male Pain Rats Rats, Sprague-Dawley Tooth Injuries - metabolism Tooth Injuries - physiopathology Trigeminal ganglion Trigeminal Ganglion - metabolism Trigeminal Ganglion - physiopathology TRPA1 Cation Channel TRPA1 channel TRPC Cation Channels - metabolism Western blot
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