A Micro-Ribonucleic Acid Signature Associated With Recovery From Assist Device Support in 2 Groups of Patients With Severe Heart Failure

Objectives This study was conducted to test the hypothesis that cardiac micro-ribonucleic acid (miR) profiling in severe heart failure patients at the time of ventricular assist device (VAD) placement would differentiate those who remained VAD-dependent from those with subsequent left ventricular (L...

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Veröffentlicht in:	Journal of the American College of Cardiology 2011-11, Vol.58 (22), p.2270-2278
Hauptverfasser:	Ramani, Ravi, MD, Vela, Deborah, MD, Segura, Ana, MD, MPH, McNamara, Dennis, MD, Lemster, Bonnie, MPH, Samarendra, Vishnupriya, BS, Kormos, Robert, MD, Toyoda, Yoshiya, MD, Bermudez, Christian, MD, Frazier, O.H., MD, Moravec, Christine S., PhD, Gorcsan, John, MD, Taegtmeyer, Heinrich, MD, DPhil, McTiernan, Charles F., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiology Cardiology. Vascular system Cardiomyocytes Cardiomyopathies - genetics Cardiomyopathies - therapy Cardiomyopathy Cardiovascular Cohort Studies Drug therapy Female Gene expression Gene Expression Profiling Heart heart assist device Heart attacks Heart failure Heart Failure - genetics Heart Failure - therapy Heart failure, cardiogenic pulmonary edema, cardiac enlargement Heart-Assist Devices Humans hypertrophy Internal Medicine Male Medical sciences microRNA MicroRNAs - metabolism Microscopy, Fluorescence Myocardium - chemistry Myocytes, Cardiac - pathology Polymerase chain reaction Real-Time Polymerase Chain Reaction Recovery of Function - genetics Studies Transplants & implants Ventricular Dysfunction, Left - genetics Ventricular Dysfunction, Left - therapy
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