Inflammatory cytokine and matrix metalloproteinase expression induced by collagen-coated and uncoated polypropylene meshes in a rat model

Objective The objective of the study was to compare the influence of collagen-coated vs uncoated polypropylene meshes on the expression of genes critical for wound healing. Study Design In 54 rats, abdominal wall defects were created, repaired by polypropylene sutures, and covered by an overlay of c...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2011-07, Vol.205 (1), p.82.e1-82.e9
Hauptverfasser:	Pierce, Lisa M., DSc, Asarias, Jennifer R., MD, MS, Nguyen, Phuoc T., MD, Mings, Jamie R., MD, Gehrich, Alan P., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Wall - pathology Abdominal Wall - surgery Animals Biocompatible Materials - metabolism coated polypropylene mesh Collagen - metabolism Cytokines - genetics Gene Expression Profiling Inflammation - enzymology Inflammation - genetics Inflammation - pathology inflammatory cytokines Male matrix metalloproteinases Matrix Metalloproteinases - genetics Obstetrics and Gynecology pelvic organ prolapse Polypropylenes rat model Rats Surgical Mesh Wound Healing - genetics
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