Intimal fibrosis in human cardiac allograft vasculopathy

Abstract Human Cardiac Allograft Vasculopathy (CAV) is one of the major complications for patients after heart transplantation. It is characterized by a concentric luminal narrowing due to (neo) intimal expansion in the coronary arteries of donor hearts after heart transplantation. In this process f...

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Veröffentlicht in:	Transplant immunology 2011-09, Vol.25 (2), p.124-132
Hauptverfasser:	Huibers, Manon, De Jonge, Nicolaas, Van Kuik, Joyce, Koning, Erica Siera-De, Van Wichen, Dick, Dullens, Hub, Schipper, Marguérite, De Weger, Roel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Allergy and Immunology Allograft vasculopathy Bone Morphogenetic Protein 4 - biosynthesis Chronic rejection Female Fibrosis Heart Transplantation - adverse effects Humans Interferon-gamma - biosynthesis Macrophages Male Middle Aged Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology RNA, Messenger Stromal Cells - metabolism T-Lymphocytes - metabolism Transforming Growth Factor beta - biosynthesis Transplantation Transplantation, Homologous - adverse effects Tunica Intima - pathology Vascular Diseases - pathology
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