Synthesis and antifungal activity of compounds of the pinane series

Synthesis and antifungal activity of compounds of the pinane series

New terpenyl sulfides of the pinane series have been synthesized from (-)-β-pinene, cis- and trans-verbenols, and myrtenol. Screening for antifungal activity of the monoterpenoids of the pinane series has been carried out. The relationship between the structure and antifungal properties of the synth...

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Veröffentlicht in:Pharmaceutical chemistry journal 2009-05, Vol.43 (5), p.251-254, Article 251
Hauptverfasser: Nikitina, L. E, Startseva, V. A, Vakulenko, I. A, Khismatulina, I. M, Lisovskaya, S. A, Glushko, N. P, Fassakhov, R. S
Format: Artikel
Sprache:eng
Schlagworte:
Antifungal activity
bicyclic monoterpenoids
Medicine
monoterpenoids
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Search for New Drugs
Sulfide
terpene sulfides
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Zusammenfassung:New terpenyl sulfides of the pinane series have been synthesized from (-)-β-pinene, cis- and trans-verbenols, and myrtenol. Screening for antifungal activity of the monoterpenoids of the pinane series has been carried out. The relationship between the structure and antifungal properties of the synthesized compounds has been established.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-009-0282-3