Proinflammatory cytokine TNF-α increases the stability of hepatitis B virus X protein through NF-κB signaling

Hepatitis B virus (HBV) X protein (HBx) is a key player in HBV-induced hepatocellular carcinoma (HCC). HBx interacts with several cell signaling molecules, leading to activation of various transcription factors including nuclear factor-kappaB (NF-κB). Activated NF-κB signaling is implicated in many...

Ausführliche Beschreibung