Slow Release and Delivery of Antisense Oligonucleotide Drug by Self-Assembled Peptide Amphiphile Nanofibers

Antisense oligonucleotides provide a promising therapeutic approach for several disorders including cancer. Chemical stability, controlled release, and intracellular delivery are crucial factors determining their efficacy. Gels composed of nanofibrous peptide network have been previously suggested a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomacromolecules 2011-08, Vol.12 (8), p.3007-3014
Hauptverfasser:	Bulut, Selma, Erkal, Turan S, Toksoz, Sila, Tekinay, Ayse B, Tekinay, Turgay, Guler, Mustafa O
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisense oligonucleotides Biological and medical sciences Blotting, Western Cell Line, Tumor Circular Dichroism General pharmacology Humans Medical sciences Microscopy, Atomic Force Microscopy, Electron, Scanning Nanofibers Oligonucleotides, Antisense - administration & dosage Oligonucleotides, Antisense - pharmacokinetics Peptides - chemistry Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Real-Time Polymerase Chain Reaction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!