Major proteins related to chlortetracycline biosynthesis in a Streptomyces aureofaciens production strain studied by quantitative proteomics

Changes in synthesis and abundance of proteins associated with chlortetracycline (CTC) production in Streptomyces aureofaciens were investigated by two-dimensional polyacrylamide gel electrophoresis of proteins pulse-labelled in vivo with L-[35S]methionine. Eleven individual protein spots were selec...

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Veröffentlicht in:	Applied microbiology and biotechnology 2001-12, Vol.57 (5-6), p.717-724
Hauptverfasser:	LI, X.-M, NOVOTNA, J, VOHRADSKY, J, WEISER, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anhydrotetracycline monooxygenase Anti-Bacterial Agents - biosynthesis Bacterial Proteins - genetics Bacterial Proteins - isolation & purification Bacterial Proteins - metabolism Biological and medical sciences Biology of microorganisms of confirmed or potential industrial interest Biosynthesis Biotechnology chlortetracycline Chlortetracycline - biosynthesis Electrophoresis, Gel, Two-Dimensional elongation factor Tu Enzymes Fundamental and applied biological sciences. Psychology Gene Expression - drug effects Kinetics Microbiology Mission oriented research Oxidoreductases - genetics Oxidoreductases - isolation & purification Oxidoreductases - metabolism Oxygenases - genetics Oxygenases - isolation & purification Oxygenases - metabolism Physiology and metabolism Proteins Proteome proteomics Streptomyces aureofaciens Streptomyces aureofaciens - drug effects Streptomyces aureofaciens - genetics Streptomyces aureofaciens - metabolism Thiocyanates - pharmacology
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