Herpesviruses and immunity: The art of evasion

Herpesviruses have evolved several effective strategies to counter the host immune response. Chief among these is inhibition of the host MHC class I antigen processing and presentation pathway, thereby reducing the presentation of virus-derived epitopes on the surface of the infected cell. This revi...

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Veröffentlicht in:	Veterinary microbiology 2010-06, Vol.143 (1), p.89-100
Hauptverfasser:	Griffin, Bryan D., Verweij, Marieke C., Wiertz, Emmanuel J.H.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen presentation antigen-presenting cells biochemical pathways Biological and medical sciences cell membranes cytotoxic T-lymphocytes defense mechanisms Fundamental and applied biological sciences. Psychology Herpesviridae Herpesviridae - immunology Herpesviridae Infections - immunology Herpesviridae Infections - veterinary Herpesvirus Histocompatibility Antigens Class I - immunology host-pathogen relationships Humans Immune Evasion immunity inhibitors Killer Cells, Natural - immunology literature reviews lymphocytes major histocompatibility complex MHC class I molecule Microbiology Miscellaneous natural killer cells pathogenesis peptides physiological transport T-Lymphocytes, Cytotoxic - immunology viral diseases of animals and humans viral proteins Virology zoonoses
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