Superficial, Nodular, and Morpheiform Basal-Cell Carcinomas Exhibit Distinct Gene Expression Profiles

Basal-cell carcinoma (BCC), the most common neoplasm in humans, occurs in a variety of morphological presentations. The mechanisms of BCC development downstream of the initial genetic mutations are not well understood, and different BCC morphological presentations might exhibit distinct gene express...

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Veröffentlicht in:	Journal of investigative dermatology 2008-07, Vol.128 (7), p.1797-1805
Hauptverfasser:	Yu, Mei, Zloty, David, Cowan, Bryce, Shapiro, Jerry, Haegert, Anne, Bell, Robert H., Warshawski, Larry, Carr, Nicholas, McElwee, Kevin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Apoptosis Biological and medical sciences Carcinoma, Basal Cell - classification Carcinoma, Basal Cell - genetics Carcinoma, Basal Cell - metabolism Cyclooxygenase 2 - genetics Dermatology Disease Progression Epithelium - metabolism Female Gene Expression Profiling Humans Male MAP Kinase Signaling System Medical sciences Middle Aged Oligonucleotide Array Sequence Analysis Signal Transduction Skin - metabolism Skin Neoplasms - classification Skin Neoplasms - genetics Skin Neoplasms - metabolism Tumors of the skin and soft tissue. Premalignant lesions Wnt Proteins - physiology
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