Measuring adrenal autoantibody response: Interlaboratory concordance in the first international serum exchange for the determination of 21-hydroxylase autoantibodies

Abstract 21-hydroxylase autoantibodies (21OHAb) are the gold standard immune marker to identify patients with clinical or subclinical autoimmune Addison's disease (AAD). No assessment of interlaboratory concordance has been made for 21OHAb measurement. Serum samples from 267 patients with prima...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2011-09, Vol.140 (3), p.291-299
Hauptverfasser:	Falorni, Alberto, Chen, Shu, Zanchetta, Renato, Yu, Liping, Tiberti, Claudio, Bacosi, Maria Luisa, Furmaniak, Jadwiga, Bini, Vittorio, Dotta, Francesco, Eisenbarth, George S, Rees Smith, Bernard, Betterle, Corrado
Format:	Artikel
Sprache:	eng
Schlagworte:	Addison Disease - blood Addison Disease - diagnosis Addison Disease - immunology Adrenal insufficiency Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adult Allergy and Immunology Antibody Formation Autoantibodies - blood Autoantibodies - immunology Autoimmune Addison's disease Autoimmune polyendocrine syndrome Biological and medical sciences Biomarkers - blood Endocrinopathies Female Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Laboratories, Hospital Male Medical sciences Middle Aged Non tumoral diseases. Target tissue resistance. Benign neoplasms Observer Variation Radioimmunoassay Radioimmunoassay - standards Reproducibility of Results Standardization Steroid 21-Hydroxylase - immunology Young Adult
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