Syntheses of phenylpyrazolodiazepin-7-ones as conformationally rigid analogs of aminopyrazole amide scaffold and their antiproliferative effects on cancer cells

The synthesis of a novel series of phenylpyrazolodiazepin-7-one derivatives 7a–g, 8a–o and their antiproliferative activities against A375P melanoma cell line and U937 hematopoietic cell line were described. Recently, we have reported the syntheses and antiproliferative activities of N-(5-amino-1-(4...

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