Eczema Genetics: Current State of Knowledge and Future Goals

Multiple genetic as well as environmental factors interact in the pathogenesis of eczema. Increased understanding of genetic predisposition in atopy and eczema has directed interest toward key pathogenic mechanisms including skin barrier dysfunction. This review provides a succinct update on the cur...

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Veröffentlicht in:	Journal of investigative dermatology 2009-03, Vol.129 (3), p.543-552
Hauptverfasser:	Brown, Sara J., Irwin McLean, W.H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Dermatitis - genetics Dermatitis - metabolism Eczema - genetics Genotype Humans Intermediate Filament Proteins - genetics Intermediate Filament Proteins - metabolism Models, Biological Models, Genetic Mutation Odds Ratio Phenotype Proteinase Inhibitory Proteins, Secretory - genetics Proteinase Inhibitory Proteins, Secretory - metabolism Serine Peptidase Inhibitor Kazal-Type 5 Skin - immunology Skin - pathology Urocanic Acid - metabolism
Online-Zugang:	Volltext
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