Dynamics of procalcitonin and bacteremia in neutropenic adults with acute myeloid leukemia

Abstract Sensitive markers of infection are rare or of limited validity in neutropenic patients. Procalcitonin (PCT), a precursor protein of calcitonin, is a specific and sensitive marker of severe bacterial infections during short-term neutropenia. Because the value of PCT measurements among patien...

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Veröffentlicht in:	Leukemia research 2011-10, Vol.35 (10), p.1294-1296
Hauptverfasser:	Gac, Anne-Claire, Parienti, Jean-Jacques, Chantepie, Sylvain, Fradin, Sabine, Le Coutour, Xavier, Leclercq, Roland, Reman, Oumedaly
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Adult Aged Anti-Bacterial Agents - administration & dosage Antibiotics Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Bacteremia Bacteremia - blood Bacteremia - complications Bacteremia - microbiology Bacterial Infections - blood Bacterial Infections - complications Bacterial Infections - drug therapy Bacterial Infections - microbiology Bacterial Infections - pathology Biomarkers - blood Blood products C-Reactive Protein - analysis Calcitonin Calcitonin - blood Calcitonin Gene-Related Peptide Chemotherapy Drugs Female Fever Gram-Negative Bacteria - growth & development Gram-Positive Bacteria - growth & development Hematology, Oncology and Palliative Medicine Humans Infection Leukemia, Myeloid, Acute - blood Leukemia, Myeloid, Acute - complications Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - microbiology Leukemia, Myeloid, Acute - pathology Male Middle Aged Neutropenia Neutropenia - blood Neutropenia - etiology Neutropenia - microbiology Neutropenia - pathology Plasma levels Predictive Value of Tests Procalcitonin Prospective Studies Protein Precursors - blood Reproducibility of Results Sensitivity and Specificity Toxicity
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