Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells

Dendritic cells (DCs) are key players in initiating and directing the immune response. Therefore, their activation state and functional differentiation need to be tightly controlled. The activating stimuli and their signaling networks have long been an area of focus in DC research. Recent investigat...

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Veröffentlicht in:The Journal of immunology (1950) 2011-09, Vol.187 (6), p.2875-2884
Hauptverfasser: Posselt, Gernot, Schwarz, Harald, Duschl, Albert, Horejs-Hoeck, Jutta
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Sprache:eng
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