Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study

Summary Background New DNA-based microarray platforms enable rapid detection and species identification of many pathogens, including bacteria. We assessed the sensitivity, specificity, and turnaround time of a new molecular sepsis assay. Methods 2107 positive blood-culture samples of 3318 blood samp...

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Veröffentlicht in:	The Lancet (British edition) 2010-01, Vol.375 (9710), p.224-230
Hauptverfasser:	Tissari, Päivi, MD, Zumla, Alimuddin, Prof, Tarkka, Eveliina, MSc, Mero, Sointu, MSc, Savolainen, Laura, MSc, Vaara, Martti, MD, Aittakorpi, Anne, BEng, Laakso, Sanna, Lindfors, Merja, BLS, Piiparinen, Heli, PhD, Mäki, Minna, PhD, Carder, Caroline, FIBMS, Huggett, Jim, PhD, Gant, Vanya, Dr
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteremia Bacteremia - microbiology Bacteria Bacteria - isolation & purification Bacterial Proteins - analysis Bacteriological Techniques Biological and medical sciences Blood Blood culture Deoxyribonucleic acid DNA DNA Gyrase - analysis DNA topoisomerase DNA topoisomerase IV DNA Topoisomerase IV - analysis DNA, Bacterial - analysis Drug Resistance, Bacterial - genetics General aspects Genes, Bacterial Humans Internal Medicine Medical research Medical sciences Microbiology Nucleic Acid Amplification Techniques Observational studies Oligonucleotide Array Sequence Analysis Pathogens Penicillin-Binding Proteins Polymerase Chain Reaction Sensitivity and Specificity Sepsis Software Staphylococcus aureus
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