Inhibitor of DNA binding-1 induces mesenchymal features and promotes invasiveness in thyroid tumour cells

Abstract Characterisation of molecular mechanisms that control tumour invasion is a crucial step for the identification of molecular markers to apply in cancer diagnosis and treatment. In this work, we have investigated the role of Id1 in thyroid tumours. We demonstrate that Id1 participates to tumo...

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Veröffentlicht in:	European journal of cancer (1990) 2011-04, Vol.47 (6), p.934-945
Hauptverfasser:	Ciarrocchi, Alessia, Piana, Simonetta, Valcavi, Roberto, Gardini, Giorgio, Casali, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Follicular Biological and medical sciences Biomarkers, Tumor - metabolism Cell Line, Tumor Cell Transformation, Neoplastic Hematology, Oncology and Palliative Medicine Humans Id1 Inhibitor of Differentiation Protein 1 - metabolism Inhibitor of Differentiation Protein 1 - physiology Invasion Medical sciences Mesenchymal markers Microenvironment Neoplasm Invasiveness Pharmacology. Drug treatments Phenotype Reverse Transcriptase Polymerase Chain Reaction Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology Thyroid tumour Tumors
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