Use of iodine-123 metaiodobenzylguanidine scintigraphy for the detection of amiodarone induced pulmonary toxicity in a rabbit model: a comparative study with technetium-99m diethyltriaminepenta acetic acid radioaerosol scintigraphy

The purpose of the study was; (i) to determine whether 123I-MIBG scintigraphy is sensitive for detection of amiodarone induced pulmonary toxicity (AIPT) and (ii) to compare it with 99mTc-DTPA radioaerosol. Twelve white New Zealand rabbit with initial mean body weight 4.24 +/- 0.47 g were divided int...

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Veröffentlicht in:	Annals of nuclear medicine 2005-05, Vol.19 (3), p.217-224
Hauptverfasser:	Durmuş-Altun, Gulay, Altun, Armagan, Aktas, Ranan Gülhan, Salihoglu, Yavuz Sami, Yigitbasi, Necmi Omer
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Iodobenzylguanidine Acetic acid Aerosols Amiodarone Amiodarone - adverse effects Amiodarone - therapeutic use Animals Anti-Arrhythmia Agents - adverse effects Anti-Arrhythmia Agents - therapeutic use Body weight Comparative studies Inhalation Injections, Intravenous Iodine Iodine isotopes Lung - diagnostic imaging Lung - drug effects Lung - pathology Lung Diseases - chemically induced Lung Diseases - diagnostic imaging Lung Diseases - pathology Lungs Mediastinum Medical imaging Pharmaceuticals Rabbits Radiochemistry Radioisotopes Radionuclide Imaging Radiopharmaceuticals Reproducibility of Results Respiration Scintigraphy Sensitivity and Specificity Technetium Technetium isotopes Technetium Tc 99m Pentetate Thorax Toxicity
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