Raloxifene for prevention of glucocorticoid-induced bone loss: a 12-month randomised double-blinded placebo-controlled trial

Objectives To study the efficacy of raloxifene in preventing bone mineral density (BMD) loss in women receiving long-term glucocorticoids (GC). The study took the form of a parallel-group randomised double-blinded placebo-controlled trial. Methods Postmenopausal women without hypercoagulability risk...

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Veröffentlicht in:	Annals of the rheumatic diseases 2011-05, Vol.70 (5), p.778-784
Hauptverfasser:	Mok, Chi Chiu, Ying, King Yee, To, Chi Hung, Ho, Ling Yin, Yu, Ka Lung, Lee, Hon Kit, Ma, Kwok Man
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers - metabolism Bone Density - drug effects Bone Density Conservation Agents - adverse effects Bone Density Conservation Agents - therapeutic use Cholesterol Diseases of the osteoarticular system Double-Blind Method Drug Administration Schedule Female Fractures Glucocorticoids - administration & dosage Glucocorticoids - adverse effects Glucocorticoids - therapeutic use Hip Joint - physiopathology Humans Lipids - blood Lumbar Vertebrae - physiopathology Medical sciences Middle Aged Osteoporosis Osteoporosis, Postmenopausal - chemically induced Osteoporosis, Postmenopausal - physiopathology Osteoporosis, Postmenopausal - prevention & control Osteoporosis. Osteomalacia. Paget disease Prednisone - administration & dosage Prednisone - adverse effects Prednisone - therapeutic use Raloxifene Hydrochloride - adverse effects Raloxifene Hydrochloride - therapeutic use Rheumatic Diseases - drug therapy Studies Thromboembolism Womens health
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