Scaffolding pre-assembled contigs using SSPACE

De novo assembly tools play a main role in reconstructing genomes from next-generation sequencing (NGS) data and usually yield a number of contigs. Using paired-read sequencing data it is possible to assess the order, distance and orientation of contigs and combine them into so-called scaffolds. Alt...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2011-02, Vol.27 (4), p.578-579
Hauptverfasser:	BOETZER, Marten, HENKEL, Christiaan V, JANSEN, Hans J, BUTLER, Derek, PIROVANO, Walter
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Contig Mapping Fundamental and applied biological sciences. Psychology Gene Library General aspects Genome Genomics - methods Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Sequence Analysis, DNA - methods Software
Online-Zugang:	Volltext
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