Memory performance in acute and weight-restored anorexia nervosa patients
Anorexia nervosa (AN), at the stage of starvation and emaciation, is characterized by abnormalities in cognitive function, including memory performance. It is unclear whether memory impairment persists or is reversible following weight restoration, and whether memory function differs between AN subt...
Gespeichert in:
| Veröffentlicht in: | Psychological medicine 2011-04, Vol.41 (4), p.829-838 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 838 |
|---|---|
| container_issue | 4 |
| container_start_page | 829 |
| container_title | Psychological medicine |
| container_volume | 41 |
| creator | Nikendei, C. Funiok, C. Pfüller, U. Zastrow, A. Aschenbrenner, S. Weisbrod, M. Herzog, W. Friederich, H.-C. |
| description | Anorexia nervosa (AN), at the stage of starvation and emaciation, is characterized by abnormalities in cognitive function, including memory performance. It is unclear whether memory impairment persists or is reversible following weight restoration, and whether memory function differs between AN subtypes. The aim of the present study was to investigate general memory performance in currently ill and fully weight-restored patients of different AN subtypes.
Memory performance was assessed using the Wechsler Memory Scale-Revised (WMS-R) in a total of 99 participants, including 34 restricting-type AN patients (AN-RESTR), 19 binge-eating/purging-type AN patients (AN-PURGE), 16 weight-restored AN patients (AN-W-R) and 30 healthy controls (CONTROL). Cognitive evaluation included a battery of standardized neuropsychological tasks for validating the findings on memory function.
Deficits were found with respect to immediate and delayed story recall in currently ill AN patients irrespective of AN subtype. These deficits persisted in weight-restored AN patients. Currently ill and weight-restored AN patients did not differ significantly from healthy controls with respect to working memory or other measures of neuropsychological functioning.
The findings suggest that impaired memory performance is either a stable trait characteristic or a scar effect of chronic starvation that may play a role in the development and/or persistence of the disorder. |
| doi_str_mv | 10.1017/S0033291710001121 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_904465815</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_S0033291710001121</cupid><sourcerecordid>2275329691</sourcerecordid><originalsourceid>FETCH-LOGICAL-c465t-bfb0cb1224de78cc9fe6ffb1476983e9a026df35999aa5dedac0ec337de509223</originalsourceid><addsrcrecordid>eNqFkU1LxDAQhoMouq7-AC9SBPFUzSRt2hxF_FhQPKjnkiaTtbJt16T149-bsqsLiuxpIPPMvO_kJeQA6ClQyM4eKOWcSciAUgrAYIOMIBEyzmWWb5LR0I6H_g7Z9f4lMBwStk12GE2ZTCAbkckd1q37jObobOtq1WiMqiZSuu8wUo2J3rGaPnexQ9-1Dk14C-WjUlGD7q31KpqrrsKm83tky6qZx_1lHZOnq8vHi5v49v56cnF-G-tEpF1c2pLqEhhLDGa51tKisLaEJBMy5ygVZcJYnkoplUoNGqUpas4zgymVjPExOVnsnbv2tQ-2irryGmcz1WDb-0LSJAjlkK4lc5EzFj5ErCdTLiVnAIE8-kW-tL1rwsEDJHhKYbAIC0i71nuHtpi7qlbuswBaDMkVf5ILM4fLxX1Zo_mZ-I4qAMdLQHmtZtaFrCq_4rhkiWAycHwprurSVWaKK4v_y38BPb2ukQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>853635012</pqid></control><display><type>article</type><title>Memory performance in acute and weight-restored anorexia nervosa patients</title><source>Applied Social Sciences Index & Abstracts (ASSIA)</source><source>MEDLINE</source><source>Cambridge Journals</source><creator>Nikendei, C. ; Funiok, C. ; Pfüller, U. ; Zastrow, A. ; Aschenbrenner, S. ; Weisbrod, M. ; Herzog, W. ; Friederich, H.-C.</creator><creatorcontrib>Nikendei, C. ; Funiok, C. ; Pfüller, U. ; Zastrow, A. ; Aschenbrenner, S. ; Weisbrod, M. ; Herzog, W. ; Friederich, H.-C.</creatorcontrib><description>Anorexia nervosa (AN), at the stage of starvation and emaciation, is characterized by abnormalities in cognitive function, including memory performance. It is unclear whether memory impairment persists or is reversible following weight restoration, and whether memory function differs between AN subtypes. The aim of the present study was to investigate general memory performance in currently ill and fully weight-restored patients of different AN subtypes.
Memory performance was assessed using the Wechsler Memory Scale-Revised (WMS-R) in a total of 99 participants, including 34 restricting-type AN patients (AN-RESTR), 19 binge-eating/purging-type AN patients (AN-PURGE), 16 weight-restored AN patients (AN-W-R) and 30 healthy controls (CONTROL). Cognitive evaluation included a battery of standardized neuropsychological tasks for validating the findings on memory function.
Deficits were found with respect to immediate and delayed story recall in currently ill AN patients irrespective of AN subtype. These deficits persisted in weight-restored AN patients. Currently ill and weight-restored AN patients did not differ significantly from healthy controls with respect to working memory or other measures of neuropsychological functioning.
The findings suggest that impaired memory performance is either a stable trait characteristic or a scar effect of chronic starvation that may play a role in the development and/or persistence of the disorder.</description><identifier>ISSN: 0033-2917</identifier><identifier>EISSN: 1469-8978</identifier><identifier>DOI: 10.1017/S0033291710001121</identifier><identifier>PMID: 20529417</identifier><identifier>CODEN: PSMDCO</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Anorexia ; Anorexia nervosa ; Anorexia Nervosa - psychology ; Anorexia Nervosa - therapy ; Attention ; Biological and medical sciences ; Body Weight ; Cognition Disorders - psychology ; Cognition Disorders - therapy ; Eating behavior disorders ; Female ; Humans ; Medical sciences ; Memory ; Mental Recall ; Neuropsychological functioning ; Neuropsychological Tests - statistics & numerical data ; Psychological tests ; Psychology. Psychoanalysis. Psychiatry ; Psychometrics - statistics & numerical data ; Psychopathology. Psychiatry ; Reference Values ; Scars ; Starvation ; Subtypes ; Wechsler Scales - statistics & numerical data ; Young Adult</subject><ispartof>Psychological medicine, 2011-04, Vol.41 (4), p.829-838</ispartof><rights>Copyright © Cambridge University Press 2010</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-bfb0cb1224de78cc9fe6ffb1476983e9a026df35999aa5dedac0ec337de509223</citedby><cites>FETCH-LOGICAL-c465t-bfb0cb1224de78cc9fe6ffb1476983e9a026df35999aa5dedac0ec337de509223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0033291710001121/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,12825,27901,27902,30976,30977,55603</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23924629$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20529417$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nikendei, C.</creatorcontrib><creatorcontrib>Funiok, C.</creatorcontrib><creatorcontrib>Pfüller, U.</creatorcontrib><creatorcontrib>Zastrow, A.</creatorcontrib><creatorcontrib>Aschenbrenner, S.</creatorcontrib><creatorcontrib>Weisbrod, M.</creatorcontrib><creatorcontrib>Herzog, W.</creatorcontrib><creatorcontrib>Friederich, H.-C.</creatorcontrib><title>Memory performance in acute and weight-restored anorexia nervosa patients</title><title>Psychological medicine</title><addtitle>Psychol Med</addtitle><description>Anorexia nervosa (AN), at the stage of starvation and emaciation, is characterized by abnormalities in cognitive function, including memory performance. It is unclear whether memory impairment persists or is reversible following weight restoration, and whether memory function differs between AN subtypes. The aim of the present study was to investigate general memory performance in currently ill and fully weight-restored patients of different AN subtypes.
Memory performance was assessed using the Wechsler Memory Scale-Revised (WMS-R) in a total of 99 participants, including 34 restricting-type AN patients (AN-RESTR), 19 binge-eating/purging-type AN patients (AN-PURGE), 16 weight-restored AN patients (AN-W-R) and 30 healthy controls (CONTROL). Cognitive evaluation included a battery of standardized neuropsychological tasks for validating the findings on memory function.
Deficits were found with respect to immediate and delayed story recall in currently ill AN patients irrespective of AN subtype. These deficits persisted in weight-restored AN patients. Currently ill and weight-restored AN patients did not differ significantly from healthy controls with respect to working memory or other measures of neuropsychological functioning.
The findings suggest that impaired memory performance is either a stable trait characteristic or a scar effect of chronic starvation that may play a role in the development and/or persistence of the disorder.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Anorexia</subject><subject>Anorexia nervosa</subject><subject>Anorexia Nervosa - psychology</subject><subject>Anorexia Nervosa - therapy</subject><subject>Attention</subject><subject>Biological and medical sciences</subject><subject>Body Weight</subject><subject>Cognition Disorders - psychology</subject><subject>Cognition Disorders - therapy</subject><subject>Eating behavior disorders</subject><subject>Female</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Memory</subject><subject>Mental Recall</subject><subject>Neuropsychological functioning</subject><subject>Neuropsychological Tests - statistics & numerical data</subject><subject>Psychological tests</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychometrics - statistics & numerical data</subject><subject>Psychopathology. Psychiatry</subject><subject>Reference Values</subject><subject>Scars</subject><subject>Starvation</subject><subject>Subtypes</subject><subject>Wechsler Scales - statistics & numerical data</subject><subject>Young Adult</subject><issn>0033-2917</issn><issn>1469-8978</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU1LxDAQhoMouq7-AC9SBPFUzSRt2hxF_FhQPKjnkiaTtbJt16T149-bsqsLiuxpIPPMvO_kJeQA6ClQyM4eKOWcSciAUgrAYIOMIBEyzmWWb5LR0I6H_g7Z9f4lMBwStk12GE2ZTCAbkckd1q37jObobOtq1WiMqiZSuu8wUo2J3rGaPnexQ9-1Dk14C-WjUlGD7q31KpqrrsKm83tky6qZx_1lHZOnq8vHi5v49v56cnF-G-tEpF1c2pLqEhhLDGa51tKisLaEJBMy5ygVZcJYnkoplUoNGqUpas4zgymVjPExOVnsnbv2tQ-2irryGmcz1WDb-0LSJAjlkK4lc5EzFj5ErCdTLiVnAIE8-kW-tL1rwsEDJHhKYbAIC0i71nuHtpi7qlbuswBaDMkVf5ILM4fLxX1Zo_mZ-I4qAMdLQHmtZtaFrCq_4rhkiWAycHwprurSVWaKK4v_y38BPb2ukQ</recordid><startdate>20110401</startdate><enddate>20110401</enddate><creator>Nikendei, C.</creator><creator>Funiok, C.</creator><creator>Pfüller, U.</creator><creator>Zastrow, A.</creator><creator>Aschenbrenner, S.</creator><creator>Weisbrod, M.</creator><creator>Herzog, W.</creator><creator>Friederich, H.-C.</creator><general>Cambridge University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QJ</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20110401</creationdate><title>Memory performance in acute and weight-restored anorexia nervosa patients</title><author>Nikendei, C. ; Funiok, C. ; Pfüller, U. ; Zastrow, A. ; Aschenbrenner, S. ; Weisbrod, M. ; Herzog, W. ; Friederich, H.-C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-bfb0cb1224de78cc9fe6ffb1476983e9a026df35999aa5dedac0ec337de509223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Anorexia</topic><topic>Anorexia nervosa</topic><topic>Anorexia Nervosa - psychology</topic><topic>Anorexia Nervosa - therapy</topic><topic>Attention</topic><topic>Biological and medical sciences</topic><topic>Body Weight</topic><topic>Cognition Disorders - psychology</topic><topic>Cognition Disorders - therapy</topic><topic>Eating behavior disorders</topic><topic>Female</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Memory</topic><topic>Mental Recall</topic><topic>Neuropsychological functioning</topic><topic>Neuropsychological Tests - statistics & numerical data</topic><topic>Psychological tests</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychometrics - statistics & numerical data</topic><topic>Psychopathology. Psychiatry</topic><topic>Reference Values</topic><topic>Scars</topic><topic>Starvation</topic><topic>Subtypes</topic><topic>Wechsler Scales - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nikendei, C.</creatorcontrib><creatorcontrib>Funiok, C.</creatorcontrib><creatorcontrib>Pfüller, U.</creatorcontrib><creatorcontrib>Zastrow, A.</creatorcontrib><creatorcontrib>Aschenbrenner, S.</creatorcontrib><creatorcontrib>Weisbrod, M.</creatorcontrib><creatorcontrib>Herzog, W.</creatorcontrib><creatorcontrib>Friederich, H.-C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Sociology Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Psychological medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nikendei, C.</au><au>Funiok, C.</au><au>Pfüller, U.</au><au>Zastrow, A.</au><au>Aschenbrenner, S.</au><au>Weisbrod, M.</au><au>Herzog, W.</au><au>Friederich, H.-C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Memory performance in acute and weight-restored anorexia nervosa patients</atitle><jtitle>Psychological medicine</jtitle><addtitle>Psychol Med</addtitle><date>2011-04-01</date><risdate>2011</risdate><volume>41</volume><issue>4</issue><spage>829</spage><epage>838</epage><pages>829-838</pages><issn>0033-2917</issn><eissn>1469-8978</eissn><coden>PSMDCO</coden><abstract>Anorexia nervosa (AN), at the stage of starvation and emaciation, is characterized by abnormalities in cognitive function, including memory performance. It is unclear whether memory impairment persists or is reversible following weight restoration, and whether memory function differs between AN subtypes. The aim of the present study was to investigate general memory performance in currently ill and fully weight-restored patients of different AN subtypes.
Memory performance was assessed using the Wechsler Memory Scale-Revised (WMS-R) in a total of 99 participants, including 34 restricting-type AN patients (AN-RESTR), 19 binge-eating/purging-type AN patients (AN-PURGE), 16 weight-restored AN patients (AN-W-R) and 30 healthy controls (CONTROL). Cognitive evaluation included a battery of standardized neuropsychological tasks for validating the findings on memory function.
Deficits were found with respect to immediate and delayed story recall in currently ill AN patients irrespective of AN subtype. These deficits persisted in weight-restored AN patients. Currently ill and weight-restored AN patients did not differ significantly from healthy controls with respect to working memory or other measures of neuropsychological functioning.
The findings suggest that impaired memory performance is either a stable trait characteristic or a scar effect of chronic starvation that may play a role in the development and/or persistence of the disorder.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>20529417</pmid><doi>10.1017/S0033291710001121</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0033-2917 |
| ispartof | Psychological medicine, 2011-04, Vol.41 (4), p.829-838 |
| issn | 0033-2917 1469-8978 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_904465815 |
| source | Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; Cambridge Journals |
| subjects | Adolescent Adult Adult and adolescent clinical studies Anorexia Anorexia nervosa Anorexia Nervosa - psychology Anorexia Nervosa - therapy Attention Biological and medical sciences Body Weight Cognition Disorders - psychology Cognition Disorders - therapy Eating behavior disorders Female Humans Medical sciences Memory Mental Recall Neuropsychological functioning Neuropsychological Tests - statistics & numerical data Psychological tests Psychology. Psychoanalysis. Psychiatry Psychometrics - statistics & numerical data Psychopathology. Psychiatry Reference Values Scars Starvation Subtypes Wechsler Scales - statistics & numerical data Young Adult |
| title | Memory performance in acute and weight-restored anorexia nervosa patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T04%3A45%3A39IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Memory%20performance%20in%20acute%20and%20weight-restored%20anorexia%20nervosa%20patients&rft.jtitle=Psychological%20medicine&rft.au=Nikendei,%20C.&rft.date=2011-04-01&rft.volume=41&rft.issue=4&rft.spage=829&rft.epage=838&rft.pages=829-838&rft.issn=0033-2917&rft.eissn=1469-8978&rft.coden=PSMDCO&rft_id=info:doi/10.1017/S0033291710001121&rft_dat=%3Cproquest_cross%3E2275329691%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=853635012&rft_id=info:pmid/20529417&rft_cupid=10_1017_S0033291710001121&rfr_iscdi=true |