Tc-99m MDP, thallium-201 chloride and Tc-99m MAG3 renal uptake in subacute and chronic radiation nephritis compared

The authors present a comparison of the findings for thallium-201 (Tl-201), Tc-99m MAG3 and Tc-99m MDP in subacute and chronic radiation nephritis in a 9-yr-old boy who was treated by radiation therapy for alveolar rhabdomyosarcoma of the left chest wall by a radiation port that partially included t...

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Veröffentlicht in:Annals of nuclear medicine 2001-10, Vol.15 (5), p.447-449
Hauptverfasser: Degirmenci, B, Uysal, K, Bekis, R, Cetingoz, R, Kaya, G C, Durak, H
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container_end_page 449
container_issue 5
container_start_page 447
container_title Annals of nuclear medicine
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creator Degirmenci, B
Uysal, K
Bekis, R
Cetingoz, R
Kaya, G C
Durak, H
description The authors present a comparison of the findings for thallium-201 (Tl-201), Tc-99m MAG3 and Tc-99m MDP in subacute and chronic radiation nephritis in a 9-yr-old boy who was treated by radiation therapy for alveolar rhabdomyosarcoma of the left chest wall by a radiation port that partially included the left kidney. Tl-201 imaging three and six months later showed a cortical defect in the left kidney due to radiation nephritis. Tc-99m MDP scan showed increased uptake on both occasions, but more marked in the subacute period than in the chronic period. Tc-99m MAG3 showed decreased concentration and increased cortical retention three months later. Six months after the radiation therapy, a cortical defect corresponding to the cortical area that showed increased parenchymal retention was more prominent in the Tc-99m MAG3 scan. In the present case, Tc-99m MDP, Tl-201 and Tc-99m MAG3 findings may provide useful information for understanding pathophysiological damage in the kidney after radiation.
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Tl-201 imaging three and six months later showed a cortical defect in the left kidney due to radiation nephritis. Tc-99m MDP scan showed increased uptake on both occasions, but more marked in the subacute period than in the chronic period. Tc-99m MAG3 showed decreased concentration and increased cortical retention three months later. Six months after the radiation therapy, a cortical defect corresponding to the cortical area that showed increased parenchymal retention was more prominent in the Tc-99m MAG3 scan. 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subjects Alveoli
Child
Chronic Disease
Defects
Humans
Kidney - metabolism
Kidneys
Male
Medical treatment
Nephritis
Nephritis - diagnostic imaging
Nephritis - metabolism
Radiation
Radiation damage
Radiation Injuries - diagnostic imaging
Radiation therapy
Radionuclide Imaging
Radiopharmaceuticals - pharmacokinetics
Rhabdomyosarcoma
Rhabdomyosarcoma, Alveolar - radiotherapy
Ribs
Technetium Tc 99m Medronate - pharmacokinetics
Technetium Tc 99m Mertiatide - pharmacokinetics
Thallium
Thallium isotopes
Thallium Radioisotopes - pharmacokinetics
Thallium-201
title Tc-99m MDP, thallium-201 chloride and Tc-99m MAG3 renal uptake in subacute and chronic radiation nephritis compared
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