Polymorphism of the human MDR1 gene in Siberian and Central Asian populations

The multidrug resistance gene MDR1 (ABCB1) codes for a P-glycoprotein that acts as an ATP-dependent transporter and is involved in removing drugs, xenobiotics, and peptides from the cell. MDR1 is expressed in the brain, kidneys, liver, and gastrointestinal tract. The P-glycoprotein is thought to pla...

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Veröffentlicht in:	Molecular biology (New York) 2007-12, Vol.41 (6), p.894-900
Hauptverfasser:	Pels, YaR, Marusin, A V, Spiridonova, M G, Stepanov, V A
Format:	Artikel
Sprache:	eng
Schlagworte:	Genes Genetics
Online-Zugang:	Volltext
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