Chip-based cartilage oligomeric matrix protein detection in serum and synovial fluid for osteoarthritis diagnosis
We have developed a method to detect cartilage oligomeric matrix protein (COMP) as a specific biomarker of osteoarthritis (OA). In pathological conditions of the cartilage, COMP is released first into the synovial fluid (SF) and from there into the blood. Thus, measurement of COMP in the blood and S...
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Veröffentlicht in: | Analytical biochemistry 2012-01, Vol.420 (2), p.139-146 |
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