Insulin-like growth factor-1 in psoriatic plaques treated with PUVA and methotrexate

Background The pathogenesis of psoriasis is thought to depend on the activation of immune cells and their secreted cytokines, chemokines and growth factors like IGF‐1 which may contribute to the epidermal hyperplasia of psoriasis. Treatment of psoriasis with PUVA and methotrexate are associated wit...

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Veröffentlicht in:	Journal of the European Academy of Dermatology and Venereology 2011-11, Vol.25 (11), p.1288-1294
Hauptverfasser:	El-Komy, M., Amin, I., Zidan, A., Kadry, D., Zeid, O.A., Shaker, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Case-Control Studies DNA Primers epidermal hyperplasia Female growth factors Humans IGF-1 Immunosuppressive Agents - therapeutic use Insulin-Like Growth Factor I - genetics Insulin-Like Growth Factor I - metabolism Male methotrexate Methotrexate - therapeutic use Photochemotherapy Polymerase Chain Reaction psoriasis Psoriasis - drug therapy Psoriasis - metabolism PUVA RNA, Messenger - genetics
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