Effect of 7-valent pneumococcal conjugate vaccine on nasopharyngeal carriage with Haemophilus influenzae and Moraxella catarrhalis in a randomized controlled trial

Abstract Seven-valent CRM197-conjugated pneumococcal conjugate vaccine (PCV7CRM197 ) reduces both vaccine serotype nasopharyngeal colonization and vaccine serotype acute otitis media by 50–60%. However, overall pneumococcal carriage and impact on otitis media are partly offset by concomitant increas...

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Veröffentlicht in:	Vaccine 2011-10, Vol.29 (44), p.7595-7598
Hauptverfasser:	van Gils, Elske J.M, Veenhoven, Reinier H, Rodenburg, Gerwin D, Hak, Eelko, Sanders, Elisabeth A.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Antibiotics Applied microbiology Bacteriology Biological and medical sciences Carriage Carrier State - epidemiology Carrier State - microbiology Child, Preschool children Children & youth Colonization Female Fundamental and applied biological sciences. Psychology Haemophilus influenzae Haemophilus influenzae - isolation & purification Heptavalent Pneumococcal Conjugate Vaccine Humans Immunization Infant Infants Male Microbiology Miscellaneous Moraxella (Branhamella) catarrhalis - isolation & purification Moraxella catarrhalis Nasopharynx - microbiology Otitis media pathogens Pneumococcal conjugate vaccine Pneumococcal Vaccines - immunology Pneumonia randomized clinical trials Replacement serotypes Streptococcus pneumoniae Streptococcus pneumoniae - isolation & purification Studies Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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