Metabolic engineering of Escherichia coli for α-farnesene production

Sesquiterpenes are important materials in pharmaceuticals and industry. Metabolic engineering has been successfully used to produce these valuable compounds in microbial hosts. However, the microbial potential of sesquiterpene production is limited by the poor heterologous expression of plant sesqui...

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Veröffentlicht in:	Metabolic engineering 2011-11, Vol.13 (6), p.648-655
Hauptverfasser:	Wang, Chonglong, Yoon, Sang-Hwal, Jang, Hui-Jeong, Chung, Young-Ryun, Kim, Jae-Yean, Choi, Eui-Sung, Kim, Seon-Won
Format:	Artikel
Sprache:	eng
Schlagworte:	Codon Codon optimization Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism FPP synthesis Geranyltranstransferase - genetics Geranyltranstransferase - metabolism Metabolic Engineering Mevalonate pathway Organisms, Genetically Modified Protein fusion Pyrophosphatases - genetics Pyrophosphatases - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Sesquiterpenes - metabolism α-Farnesene
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