Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers
Stem cells that can be directed to differentiate into specific cell types offer the prospect of a renewable source of replacement cells to treat diseases. This study evaluates the reprogramming of 2 readily available stem cell populations into skeletal muscle. We show for the first time that freshly...
Gespeichert in:
| Veröffentlicht in: | Translational research : the journal of laboratory and clinical medicine 2011-12, Vol.158 (6), p.334-343 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 343 |
|---|---|
| container_issue | 6 |
| container_start_page | 334 |
| container_title | Translational research : the journal of laboratory and clinical medicine |
| container_volume | 158 |
| creator | Collins-Hooper, Henry Luke, Graham Cranfield, Mark Otto, William R Ray, Steve Patel, Ketan |
| description | Stem cells that can be directed to differentiate into specific cell types offer the prospect of a renewable source of replacement cells to treat diseases. This study evaluates the reprogramming of 2 readily available stem cell populations into skeletal muscle. We show for the first time that freshly isolated muscle fibers reprogram bone marrow or white fat stem cells far more efficiently than muscle cell lines. In addition, we show that the ability of muscle fibers to reprogram stem cells can be almost doubled through the use of chromatin remodeling reagents such as trichostatin A. This novel approach permits the generation of myogenic cells that could be used to treat a range of muscle-wasting diseases. |
| doi_str_mv | 10.1016/j.trsl.2011.07.009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_902811305</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S193152441100260X</els_id><sourcerecordid>902811305</sourcerecordid><originalsourceid>FETCH-LOGICAL-c440t-2b147bdb601b939e9a6e2c564e1c32d5dcc053a3ab3438a9e678172274e149de3</originalsourceid><addsrcrecordid>eNp9kk2LFDEQhhtR3HX0D3iQXMRTj1XpTH-ACLKsH7DgQQVvIZ2uns1suntNpV367g83zYwfePCUQJ56ST1VWfYUYYuA5cvDNgb2WwmIW6i2AM297Bzrqs6xRrif7k2B-U4qdZY9Yj4AqLIB9TA7kxJKBIXn2Y_LvnfW0RjFsEx7Gp0VgW7DtA9mGNy4F1MvTDf7KO6uXSTRmyg40iAsec_CjJ1op5HEYEKY7v5-ahfRB-JrvwjHkzeROsE35CkaL4aZrU9prqXAj7MHvfFMT07nJvvy9vLzxfv86uO7DxdvrnKrFMRctqiqtmtLwLYpGmpMSdLuSkVoC9ntOmthV5jCtIUqatNQWdVYSVklQDUdFZvsxTE39fdtJo56cLx-1ow0zawbkDVikUI2mTySNkzMgXp9G1xqcdEIepWvD3qVr1f5Giqd5KeiZ6f4uR2o-13yy3YCnp8Aw9b4PpjROv7DqaqCUtWJe3XkKMn47ihoXkdkqXOBbNTd5P7_j9f_lFvv0mCNv6GF-DDNYUyaNWqWGvSndU3WLUEEkCV8LX4Ckc25uQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>902811305</pqid></control><display><type>article</type><title>Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Collins-Hooper, Henry ; Luke, Graham ; Cranfield, Mark ; Otto, William R ; Ray, Steve ; Patel, Ketan</creator><creatorcontrib>Collins-Hooper, Henry ; Luke, Graham ; Cranfield, Mark ; Otto, William R ; Ray, Steve ; Patel, Ketan</creatorcontrib><description>Stem cells that can be directed to differentiate into specific cell types offer the prospect of a renewable source of replacement cells to treat diseases. This study evaluates the reprogramming of 2 readily available stem cell populations into skeletal muscle. We show for the first time that freshly isolated muscle fibers reprogram bone marrow or white fat stem cells far more efficiently than muscle cell lines. In addition, we show that the ability of muscle fibers to reprogram stem cells can be almost doubled through the use of chromatin remodeling reagents such as trichostatin A. This novel approach permits the generation of myogenic cells that could be used to treat a range of muscle-wasting diseases.</description><identifier>ISSN: 1931-5244</identifier><identifier>EISSN: 1878-1810</identifier><identifier>DOI: 10.1016/j.trsl.2011.07.009</identifier><identifier>PMID: 22061041</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Adipose Tissue, White - cytology ; Adult Stem Cells - cytology ; Animals ; Biological and medical sciences ; Bone Marrow Cells - cytology ; Cell Communication - physiology ; Cell Differentiation - drug effects ; Cell Differentiation - physiology ; Cells, Cultured ; Female ; General aspects ; Green Fluorescent Proteins - genetics ; Internal Medicine ; Intra-Abdominal Fat - cytology ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Mesenchymal Stem Cell Transplantation ; Mesenchymal Stromal Cells - cytology ; Muscle Development - physiology ; Muscle Fibers, Skeletal - cytology ; Muscular Atrophy - pathology ; Muscular Atrophy - therapy ; Rats ; Rats, Transgenic ; Rats, Wistar</subject><ispartof>Translational research : the journal of laboratory and clinical medicine, 2011-12, Vol.158 (6), p.334-343</ispartof><rights>Mosby, Inc.</rights><rights>2011 Mosby, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-2b147bdb601b939e9a6e2c564e1c32d5dcc053a3ab3438a9e678172274e149de3</citedby><cites>FETCH-LOGICAL-c440t-2b147bdb601b939e9a6e2c564e1c32d5dcc053a3ab3438a9e678172274e149de3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S193152441100260X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24770648$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22061041$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Collins-Hooper, Henry</creatorcontrib><creatorcontrib>Luke, Graham</creatorcontrib><creatorcontrib>Cranfield, Mark</creatorcontrib><creatorcontrib>Otto, William R</creatorcontrib><creatorcontrib>Ray, Steve</creatorcontrib><creatorcontrib>Patel, Ketan</creatorcontrib><title>Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers</title><title>Translational research : the journal of laboratory and clinical medicine</title><addtitle>Transl Res</addtitle><description>Stem cells that can be directed to differentiate into specific cell types offer the prospect of a renewable source of replacement cells to treat diseases. This study evaluates the reprogramming of 2 readily available stem cell populations into skeletal muscle. We show for the first time that freshly isolated muscle fibers reprogram bone marrow or white fat stem cells far more efficiently than muscle cell lines. In addition, we show that the ability of muscle fibers to reprogram stem cells can be almost doubled through the use of chromatin remodeling reagents such as trichostatin A. This novel approach permits the generation of myogenic cells that could be used to treat a range of muscle-wasting diseases.</description><subject>Adipose Tissue, White - cytology</subject><subject>Adult Stem Cells - cytology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow Cells - cytology</subject><subject>Cell Communication - physiology</subject><subject>Cell Differentiation - drug effects</subject><subject>Cell Differentiation - physiology</subject><subject>Cells, Cultured</subject><subject>Female</subject><subject>General aspects</subject><subject>Green Fluorescent Proteins - genetics</subject><subject>Internal Medicine</subject><subject>Intra-Abdominal Fat - cytology</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Mesenchymal Stem Cell Transplantation</subject><subject>Mesenchymal Stromal Cells - cytology</subject><subject>Muscle Development - physiology</subject><subject>Muscle Fibers, Skeletal - cytology</subject><subject>Muscular Atrophy - pathology</subject><subject>Muscular Atrophy - therapy</subject><subject>Rats</subject><subject>Rats, Transgenic</subject><subject>Rats, Wistar</subject><issn>1931-5244</issn><issn>1878-1810</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk2LFDEQhhtR3HX0D3iQXMRTj1XpTH-ACLKsH7DgQQVvIZ2uns1suntNpV367g83zYwfePCUQJ56ST1VWfYUYYuA5cvDNgb2WwmIW6i2AM297Bzrqs6xRrif7k2B-U4qdZY9Yj4AqLIB9TA7kxJKBIXn2Y_LvnfW0RjFsEx7Gp0VgW7DtA9mGNy4F1MvTDf7KO6uXSTRmyg40iAsec_CjJ1op5HEYEKY7v5-ahfRB-JrvwjHkzeROsE35CkaL4aZrU9prqXAj7MHvfFMT07nJvvy9vLzxfv86uO7DxdvrnKrFMRctqiqtmtLwLYpGmpMSdLuSkVoC9ntOmthV5jCtIUqatNQWdVYSVklQDUdFZvsxTE39fdtJo56cLx-1ow0zawbkDVikUI2mTySNkzMgXp9G1xqcdEIepWvD3qVr1f5Giqd5KeiZ6f4uR2o-13yy3YCnp8Aw9b4PpjROv7DqaqCUtWJe3XkKMn47ihoXkdkqXOBbNTd5P7_j9f_lFvv0mCNv6GF-DDNYUyaNWqWGvSndU3WLUEEkCV8LX4Ckc25uQ</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>Collins-Hooper, Henry</creator><creator>Luke, Graham</creator><creator>Cranfield, Mark</creator><creator>Otto, William R</creator><creator>Ray, Steve</creator><creator>Patel, Ketan</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers</title><author>Collins-Hooper, Henry ; Luke, Graham ; Cranfield, Mark ; Otto, William R ; Ray, Steve ; Patel, Ketan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-2b147bdb601b939e9a6e2c564e1c32d5dcc053a3ab3438a9e678172274e149de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adipose Tissue, White - cytology</topic><topic>Adult Stem Cells - cytology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Bone Marrow Cells - cytology</topic><topic>Cell Communication - physiology</topic><topic>Cell Differentiation - drug effects</topic><topic>Cell Differentiation - physiology</topic><topic>Cells, Cultured</topic><topic>Female</topic><topic>General aspects</topic><topic>Green Fluorescent Proteins - genetics</topic><topic>Internal Medicine</topic><topic>Intra-Abdominal Fat - cytology</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Mesenchymal Stem Cell Transplantation</topic><topic>Mesenchymal Stromal Cells - cytology</topic><topic>Muscle Development - physiology</topic><topic>Muscle Fibers, Skeletal - cytology</topic><topic>Muscular Atrophy - pathology</topic><topic>Muscular Atrophy - therapy</topic><topic>Rats</topic><topic>Rats, Transgenic</topic><topic>Rats, Wistar</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Collins-Hooper, Henry</creatorcontrib><creatorcontrib>Luke, Graham</creatorcontrib><creatorcontrib>Cranfield, Mark</creatorcontrib><creatorcontrib>Otto, William R</creatorcontrib><creatorcontrib>Ray, Steve</creatorcontrib><creatorcontrib>Patel, Ketan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Translational research : the journal of laboratory and clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Collins-Hooper, Henry</au><au>Luke, Graham</au><au>Cranfield, Mark</au><au>Otto, William R</au><au>Ray, Steve</au><au>Patel, Ketan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers</atitle><jtitle>Translational research : the journal of laboratory and clinical medicine</jtitle><addtitle>Transl Res</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>158</volume><issue>6</issue><spage>334</spage><epage>343</epage><pages>334-343</pages><issn>1931-5244</issn><eissn>1878-1810</eissn><abstract>Stem cells that can be directed to differentiate into specific cell types offer the prospect of a renewable source of replacement cells to treat diseases. This study evaluates the reprogramming of 2 readily available stem cell populations into skeletal muscle. We show for the first time that freshly isolated muscle fibers reprogram bone marrow or white fat stem cells far more efficiently than muscle cell lines. In addition, we show that the ability of muscle fibers to reprogram stem cells can be almost doubled through the use of chromatin remodeling reagents such as trichostatin A. This novel approach permits the generation of myogenic cells that could be used to treat a range of muscle-wasting diseases.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>22061041</pmid><doi>10.1016/j.trsl.2011.07.009</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1931-5244 |
| ispartof | Translational research : the journal of laboratory and clinical medicine, 2011-12, Vol.158 (6), p.334-343 |
| issn | 1931-5244 1878-1810 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_902811305 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adipose Tissue, White - cytology Adult Stem Cells - cytology Animals Biological and medical sciences Bone Marrow Cells - cytology Cell Communication - physiology Cell Differentiation - drug effects Cell Differentiation - physiology Cells, Cultured Female General aspects Green Fluorescent Proteins - genetics Internal Medicine Intra-Abdominal Fat - cytology Investigative techniques, diagnostic techniques (general aspects) Medical sciences Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - cytology Muscle Development - physiology Muscle Fibers, Skeletal - cytology Muscular Atrophy - pathology Muscular Atrophy - therapy Rats Rats, Transgenic Rats, Wistar |
| title | Efficient myogenic reprogramming of adult white fat stem cells and bone marrow stem cells by freshly isolated skeletal muscle fibers |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T10%3A34%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Efficient%20myogenic%20reprogramming%20of%20adult%20white%20fat%20stem%20cells%20and%20bone%20marrow%20stem%20cells%20by%20freshly%20isolated%20skeletal%20muscle%20fibers&rft.jtitle=Translational%20research%20:%20the%20journal%20of%20laboratory%20and%20clinical%20medicine&rft.au=Collins-Hooper,%20Henry&rft.date=2011-12-01&rft.volume=158&rft.issue=6&rft.spage=334&rft.epage=343&rft.pages=334-343&rft.issn=1931-5244&rft.eissn=1878-1810&rft_id=info:doi/10.1016/j.trsl.2011.07.009&rft_dat=%3Cproquest_cross%3E902811305%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=902811305&rft_id=info:pmid/22061041&rft_els_id=1_s2_0_S193152441100260X&rfr_iscdi=true |