Atherosclerosis: current pathogenesis and therapeutic options

Coronary artery disease (CAD) arising from atherosclerosis is a leading cause of death and morbidity worldwide. The underlying pathogenesis involves an imbalanced lipid metabolism and a maladaptive immune response entailing a chronic inflammation of the arterial wall. The disturbed equilibrium of li...

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Veröffentlicht in:	Nature medicine 2011-11, Vol.17 (11), p.1410-1422
Hauptverfasser:	Weber, Christian, Noels, Heidi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154/309/555 692/420 692/699/75/593/15 692/699/75/593/2100 Adaptive Immunity Atherosclerosis Atherosclerosis - complications Atherosclerosis - drug therapy Atherosclerosis - pathology Atherosclerosis - physiopathology B-Lymphocytes - immunology Biomedical and Life Sciences Biomedicine Cancer Research Care and treatment Causes of Chemokines - immunology Coronary Artery Disease - drug therapy Coronary Artery Disease - etiology Coronary Artery Disease - pathology Coronary Artery Disease - physiopathology Dendritic Cells - immunology Development and progression Diagnosis Drug therapy Genetics Health aspects Homeostasis Humans Immune response Immunity, Innate Infectious Diseases Inflammation - pathology Inflammation - physiopathology Lipid Metabolism Lipids Metabolic Diseases Molecular Medicine Morbidity Neurosciences Neutrophils - physiology Pathology Pharmacology Physiological aspects Receptors, Chemokine - immunology review-article T-Lymphocytes - immunology
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