Association Analysis Between Variants in Bovine Progesterone Receptor Gene and Superovulation Traits in Chinese Holstein Cows

Association Analysis Between Variants in Bovine Progesterone Receptor Gene and Superovulation Traits in Chinese Holstein Cows

Contents The objective of this study was to identify a predictor to forecast superovulation response on the basis of associations between superovulation performance and gene polymorphism. The PCR‐RFLP method was applied to detect two reported single nucleotide polymorphisms (SNPs) of G59752C and T81...

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Veröffentlicht in:Reproduction in domestic animals 2011-12, Vol.46 (6), p.1029-1034
Hauptverfasser: Yang, WC, Tang, KQ, Li, SJ, Yang, LG
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Breeding of animals
Cattle
Cattle - genetics
Cattle - physiology
Fundamental and applied biological sciences. Psychology
Genetic Variation
Genotype
Mammalian reproduction. General aspects
Polymerase Chain Reaction - veterinary
Polymorphism
Polymorphism, Restriction Fragment Length
Progesterone
Receptors, Progesterone - genetics
Receptors, Progesterone - metabolism
Selective breeding
Superovulation - drug effects
Superovulation - genetics
Superovulation - physiology
Vertebrates: reproduction
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Zusammenfassung:Contents The objective of this study was to identify a predictor to forecast superovulation response on the basis of associations between superovulation performance and gene polymorphism. The PCR‐RFLP method was applied to detect two reported single nucleotide polymorphisms (SNPs) of G59752C and T81637C (rs41614030) located in introns 3 and 4 of the bovine progesterone receptor (PGR) gene in 171 Chinese Holstein cows treated for superovulation and evaluate its associations with superovulation traits. In polymorphic locus 81637, all cows without superovulation response were g.81637TC and g.81637TT genotypes. Association analysis showed that these two SNPs had significant effects on the total number of ova (TNO) (p 
ISSN:0936-6768
1439-0531
DOI:10.1111/j.1439-0531.2011.01780.x