Kinetic efficiency: the missing metric for enhancing compound quality?

The kinetics of ligand–target interactions have been recognised as being instrumental in dictating the efficacy of drug action. Increased focus on kinetic signatures in drug discovery has concincided with improvements in label free methodology for measuring kinetic parameters. Simultaneously, focus...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Drug discovery today 2011-11, Vol.16 (21), p.910-913
Hauptverfasser:	Holdgate, Geoffrey A., Gill, Adrian L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Drug Compounding Drug Discovery Efficiency General pharmacology Humans Ligands Medical sciences Molecular Targeted Therapy Pharmaceutical Preparations - metabolism Pharmaceutical technology. Pharmaceutical industry Pharmacokinetics Pharmacology. Drug treatments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!