Two classes of silencing RNAs move between Caenorhabditis elegans tissues

Organism-wide RNA interference (RNAi) is due to the movement of mobile RNA species throughout the organism. New genetic evidence shows that double-stranded RNA (dsRNA), which triggers RNAi, and at least one dsRNA intermediate produced during RNAi can act as or generate mobile silencing RNAs in Caeno...

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Veröffentlicht in:	Nature structural & molecular biology 2011-11, Vol.18 (11), p.1184-1188
Hauptverfasser:	Jose, Antony M, Garcia, Giancarlo A, Hunter, Craig P
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337/176/2016 631/337/384/2053 631/337/505 Animals Biochemistry Biological Microscopy Biomedical and Life Sciences Caenorhabditis elegans Caenorhabditis elegans - anatomy & histology Caenorhabditis elegans - genetics Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Genetic aspects Genetics Life Sciences Membrane Biology Physiological aspects Plants - genetics Protein Structure Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Ribonucleic acid RNA RNA Interference RNA polymerases RNA, Double-Stranded - genetics RNA, Double-Stranded - metabolism RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Tissues Worms
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